[目的]总结魏跃钢教授治疗寻常型银屑病(psoriasis)血热证的临床经验。[方法]通过对典型验案的分析,阐述魏教授治疗寻常型银屑病血热证的辨证思想和临床用药经验。[结果]寻常型银屑病病机中,病位重于血分,其发病的起始阶段以血热为主;临床治疗寻常型银屑病进行期的主要治则为"清热凉血解毒";用自拟方"凉血解毒饮"治疗。案例中患者经治疗皮疹基本消退,诸症缓解。[结论]魏跃钢教授治疗寻常型银屑病血热证,疗效显著,对临床实践具有指导意义。

Objective To sum up Pro. Wei Yuegang''s clinical experience in treating psoriasis vulgaris of hot blood syndrome. [Method] By analysis to classical recipe cases, it states Pro. Wei''s differentiation thought and clinical medication experience in treating psoriasis vulgaris of hot blood. [Result] In the mechanism of the disease, the location is in blood, in the first stage, it shows hot blood mainly; the clinical treatment centers on “clearing heat to cool blood and remove toxin”in the development stage, by using his own“Liangxue Jiedu Drink”. In the case here, the patient basical y disappeared the acne, his al symptoms were relieved. [Conclusion] Pro. Wei Yuegang has good cure effect on treating psoriasis vulgaris of hot blood with differentiation of signs, with guiding meaning to practical clinic.

目的研究HBD-2在寻常疣中表达和意义。方法采用免疫组化SP法检测25例寻常疣皮损组织、20例寻常型银屑病皮损组织、15例正常人皮肤组织石蜡标本中HBD-2在皮损中表达。结果寻常疣患者与银屑病患者相比，HBD-2水平低于银屑病阳性对照组，较正常人皮肤组织表达高，差异均有统计学意义（P＜0.05）。结论 HBD-2可能参与寻常疣免疫调节过程，并在发病机制中起一定作用。

Objective To explore the expressions and significance of HBD-2 in the verruca vulgaris. Methods Twenty five samples of verruca vulgaris skin, twenty samples of psorias vulgaris and fifteen samples of normal skin were analyzed by Elivision immunohistochemical technique for the expressions of HBD-2. Results Compared with those of psorias vulgaris , HBD-2 were more lowly expressions in the verruca vulgaris. The expression of HBD-2 was higher than in the normal skin. (all P<0.05).Conclusion HBD-2 may participate in verruca vulgar immune adjustment process,and be involved in the pathogenesis of verruca vulgaris.

目的通过对356例寻常型痤疮患者的中医体质调查,探讨寻常型痤疮患者的体质类型特点。方法采用《中医体质分类与判定表》测评356例寻常型痤疮患者得分,分析患者体质类型的分布规律。结果寻常型痤疮患者属湿热质最多;女性较男性偏颇气虚质、阳虚质、瘀血质、气郁质及特禀质(P0.05);皮损以上部为主受累者偏颇为痰湿质增加;皮损以中部为主受累者偏颇为湿热质、瘀血质增加;皮损以左右为主受累者偏颇为气郁质、瘀血质增加;皮损以下部为主受累者偏颇为阴虚质增加,差异均有统计学意义(P0.05)。结论寻常型痤疮的形成与中医体质类型的偏颇有关,辨体与辨证论治相结合可为临床实践提供更好的辨治思路。

Objective To investigate constitutional types of patients who suffered acne vulgaris and analyze the characteristics of acne patients .Methods The standardized Constitution in Chinese Medicine Questionnaire was answered by 356 patients to evaluate the scores of all kinds of constitutional types and the distribution rules of consti -tutional types in acne patients .Results Among the acne patients ,the most type of pathological constitutions in acne patients was wet-heat.Compared with the male patients ,the percentages of qi -deficiency,yang-deficiency,blood-stasis,qi-depression and special diathesis types were increased in the female patients .The percentage of phlegm -wetness was increased in the patients with skin lesion the upper part primarily ,the percentages of wet -heat and blood-stasis were increased in the patients with skin lesion the middle part primarily ,the percentages of qi -depression and blood-stasis were increased in the patients with skin lesion both left and right si

目的：观察白癜风皮损中CD207的表达，探讨白癜风的免疫发病机制。方法采用免疫组织化学法检测12例节段型白癜风、25例寻常型白癜风和10例正常皮肤组织中CD207的表达水平，并比较其差异性。结果节段型白癜风组、寻常型白癜风组表皮内CD207表达分别为（61.2±10.9）和（64.3±12.5）个/mm，均高于正常对照组（52.4±0.3）个/mm，差异有统计学意义（P﹤0.05）。节段型白癜风组与寻常型白癜风组相比，CD207表达差异无统计学意义（ P﹥0.05）。结论节段型白癜风、寻常型白癜风皮损组织中CD207的表达高于正常对照组，提示其发病机制与朗格汉斯细胞参与的细胞免疫反应有关。

Objective To observe the expression of CD207 in the lesions of vitiligo and the immune pathogenesis of vitiligo. Meth-ods The CD207 expression level was detected by immunohistochemistry in 12 patients with segmental vitiligo,25 patients with vitiligo vulgaris and 10 normal skin tissues,and the results were compared. Re-sults The expression of CD207 in segmental vitiligo group and vitiligo vulgaris group was(61. 2 ± 10. 9) and(64. 3 ± 12. 5)count/mm respectively,(52. 4 ± 10. 3)count/mm in control group. The differences were statistically significant( P﹤0. 05 ). Conclusions The expression of CD207 in the lesions of seg-mental vitiligo and vitiligo vulgaris is higher than that in the normal control group,indicating that the mechanism of vitiligo is associated with the cellular immunity response which langerhans cell was in-volved.

目的：比较STA-21与卡泊三醇软膏治疗寻常型银屑病的疗效。方法在26例寻常型银屑病患者对称部位选取临床表现、大小和部位相一致的皮损，分别外用0.2%STA-21软膏和卡泊三醇软膏治疗2周，记录治疗前后的PASI分值。结果治疗组有效率65.38%，高于对照组的46.15%，差异有统计学意义(P<0.001)；两组均无严重不良反应。结论 STA-21治疗寻常型银屑病的疗效较卡泊三醇好。

Objective To compare STA-21 with calcipotriol ointment in treatment of psoriasis vulgaris. Methods The lesions in 26 patients with psoriasis vulgaris symmetrical parts selected clinical manifestations, size and location are consistent, topical 0.2%STA-21 ointment and calcipotriol ointment for 2 weeks, the PASI scores were recorded before and after treatment. Results The effective rate of the treatment group was 65.38%, 46.15% in the control group, the difference was statistically significant(P<0.001). The two groups had no serious adverse reactions. Conclusion The efficacy of STA-21 in treatment of psoriasis vulgaris than card berth three alcohol.