目的通过检测并分析婴幼儿轮状病毒性肠炎与非轮状病毒感染性肠炎患儿心肌酶的水平,探讨轮状病毒感染与心肌损伤的相关性。方法 54例婴幼儿轮状病毒性肠炎的患儿作为观察组,78例轮状病毒阴性的腹泻病患儿作为对照组。两组患儿入院后抽取取空腹血清检查心肌酶[磷酸肌酸激酶(CK)及其同工酶(CK-MB)、门冬氨酸氨基转移酶(AST)]进行比较分析。两组患儿经治疗,腹泻症状消失后,将心肌酶三项均增高患儿的血清心肌酶进行治疗前后的分析比较。结果观察组中血清心肌酶三项(AST、CK-MB、CK)的水平较对照组高,差异有显著性(P0.05)。且入院时,观察组心肌酶三项均异常者有30例,占55.6%;对照组心肌酶三项均异常者有13例,占16.7%。观察组心肌酶异常者比率显著高于对照组,差异有显著性(P0.05)。治疗前,观察组心肌酶三项均异常者心肌酶水平较对照组增高,差异有显著性(P0.05);治疗后,两组心肌酶三项均异常者心肌酶水平差异无统计学意义(P0.05)。结论婴幼儿轮状病毒性肠炎较非轮状病毒性腹泻更容易导致患儿心肌的损伤,经治疗后,心肌酶可以在短时间内恢复正常。因此,在治疗婴幼儿轮状病毒性肠炎时应进行心肌酶的检测,并注意排除病毒性心肌炎。
Objective To explore the significance of serum level of myocardial enzymes in infantile patients with rotavirus enteritis. Methods A total of 132 infantile patients with diarrhea,ranging from 6 months to 3 years old admitted in 2012 were allocated in this study,54 of them with positive rotavirus antigen were listed as observation group,and 78 cases with negative rotavirous antigen as control group. Serum myo-cardial enzymes as creatine phosphate kinase(CK),creatine phosphate kinase isoenzyme(CK - MB)and aspartic transaminase(AST)were ana-lyzed and compared between these two groups before and after treatment. Results Serum levels of 3 enzymes(AST,CK - MB and CK)in obser-vation group were higher than those of control group,and the difference was statistically significant( P ﹤ 0. 05). There were 30 cases in observa-tion group with 3 kinds of abnormal cardiac enzymes accounted for 55. 6% ;and 13 cases(16. 7% )with 3 kinds of abnormal cardiac enzymes in control group. The percent
