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双语推荐:贫血病因

目的:探讨骨髓细胞学检查在贫血病因诊断中的临床价值。方法随机选取2010年1月-2012年1月来入院治疗的240例贫血病患者为研究样本,回顾性分析患者的骨髓细胞学临床资料,分析检查疗效。结果240例样本中有204例可以找到贫血的致病病因,占85%,显示了较高的诊断结果。其中,缺铁性贫血,急性白血病和再生障碍性贫血最为常见。病因。结论骨髓细胞学在检查贫血病病因诊断方面存在一定的局限性,但其对贫血的确诊、贫血类型的确定具有十分重要的临床意义,值得推广。
Objective: To discuss of the clinical value of bone marrow cytology in the etiological diagnosis of anemia. Methods: Randomly selected from January 2010 to 2012 in January to 240 cases of anemia in hospitalized patients for the study sample, recal ing the bone marrow of patients with cytological analysis of clinical data, efficacy analysis of inspection. Results: 204 cases were diagnosed (85%), the most common disease type was IDA, AL and AA. Conclusion:Though bone marrow cytology has limits in some degree, it is meaningful for diagnose of anemia and anemia type.

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综述了中医学对运动性贫血病因病机的认识、临床和实验研究现状,并对中国期刊全文数据库(CNKI)收录防治运动性贫血方剂进行数据挖掘,分析用药配伍规律,为中医药防治运动性贫血提供一定参考。
Based on the review of the understanding of Chinese traditional medicine on the etiology and pathogenesis of sports anemia,the clinical and experimental studies,and by studying the data of prevention of exercise - induced anemia included in Chinese journal full -text database(CNKI)prescription data,an analysis was made on drug compatibility rules for the prevention of exercise - induced anemia medicine.

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目的:分析老年贫血患者骨髓细胞学特点,探讨老年贫血病因,提高对老年贫血的重视。方法:回顾分析158例老年贫血患者(≥60岁)骨髓细胞学检查结果及临床资料。结果:158例老年贫血患者中轻度贫血48例(30.4%);中度贫血71例(44.9%);重度贫血39例(24.7%)。明确病因的有136例(86.1%):其中巨幼细胞性贫血26例(16.5%);慢性病贫血23例(14.6%);缺铁性贫血20例(12.7%);多发性骨髓瘤13例(8.2%);急性白血病12例(7.6%);血小板减少9例(5.7%);感染性贫血7例(4.3%);慢性淋巴细胞白血病5例(3.2%);骨髓增生异常综合征5例(3.2%);溶血性贫血4例(2.5%);淋巴瘤3例(1.9%);脾功能亢进3例(1.9%);慢性粒细胞白血病2例(1.3%);恶性肿瘤2例(1.3%);纯红再障1例(0.6%);骨髓纤维化1例(0.6%)。不明原因22例(13.9%)。结论:⑴老年贫血病因复杂、起病隐匿,多为中重度贫血,影响老年人生存寿命,应引起老年人及医务工作者的高度重视,尽早发现,明确病因,及时预防和治疗,提高老年人的生活质量。⑵骨髓细胞学检查对老年贫血的确诊、贫血类型的确定具有重要临床意义。
Objective:Cytological analysis of characteristics of the patients with bone marrow anemia in the elderly, to investigate the causes of anemia, improvement of anemia in the elderly attention.Methods:A retrospective analysis of 158 cases of anemia in the elderly patients (≥ 60 years) bone marrow cytology results and clinical data were performed.Results:158 cases of 48 cases with anemia in the elderly patients with mild anemia (30.4%); moderate anemia in 71 cases (44.9%); 39 cases (24.7%) in severe anemia. Diagnosis of 136 cases (86.1%): among the 26 cases of megaloblastic anemia (16.5%); anemia of chronic disease in 23 cases (14.6%); 20 cases with iron deficiency anemia (12.7%); 13 cases of multiple myeloma (8.2%); 12 cases of acute leukemia (7.6%); 9 patients with thrombocytopenia (5.7%); infectious anemia in 7 cases (4.3%); 5 cases of chronic lymphocytic leukemia (3.2%); 5 cases of myelodysplastic syndrome (3.2%); 4 cases of hemolytic anemia (2.5%); 3 cases of lymphoma (1.9%

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目的:探讨农村老年人巨幼细胞贫血的临床特点。方法:对我院收治的42例农村巨幼细胞贫血患者的临床资料进行回顾性分析。结果:发现农村老年巨幼细胞贫血的主要病因为消化道疾病及膳食不均衡,起病较隐匿,进展较缓慢,临床表现较多样,且易误诊。结论:农村老年人巨幼细胞贫血发生率高,注意早期防治,避免严重并发症的发生。
Objective:To explore the clinical characteristics of megaloblastic anemia ( MA) in rural elderly .Methods:A retrospectiveanalysis was done in 42 cases of Huaihe hospital elderly with MA .Result: The main causes of elderly MA disease were gastrointestinal tract diseases and unreasonable dietary , the onset caused were hidden , slow progress , diverse clinical manifestation , and it was easy to misdiagtive .Conclusion:The incidence of MA is high in elderly , with early diagnosis and treatment , avoid the severe complications .

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类风湿关节炎(RA)的发病机制及病理过程至今仍未得到确切彻底的解释。本文旨在对该病现有病理生理方面之研究成果进行再分析再归纳,结合临床,整合现有科研成果,对类风湿关节炎的病理机制(包括病因、疼痛、肿胀、晨僵、类风湿结节、关节软骨破坏、贫血等方面)进行阐述,以期在现有知识下,尽可能全面探讨和总结该病的病理机制,并指导临床实践。
Objective:The pathogenesis and pathological process of RA has not explained exactly yet. This paper aims to reanalysis and conclude present results on this field. It illustrates pathomechanism of RA combining clinic and integrating the existing scientific research, including etiology, ache, swelling, morning stiffness, rheumatoid nodules, articular cartilage damage and anemia. Consequently, it is expected to gengerally discuss pathomechanism of RA to guide clinical practice with available knowledge.

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目的:探讨分析新生儿高胆红素血症的常见原因,以提高其病因诊治水平,减少漏诊率、误诊率、致残率及致死率。方法选取我院2011年2月-2013年3月收治的符合高胆红素血症的新生儿195例,对各种常见病因进行回顾性分析。结果新生儿高胆红素血症由多种原因引起,其主要常见原因为:感染52例(26.7%)、围产期因素44例(22.6%)、ABO溶血病33例(16.9%)、葡萄糖-6-磷酸脱氢酶(G6-PD)缺乏23例(11.8%)、地中海贫血20例(10.3%)、母乳性黄疸18例(9.2%)、原因不明5例(2.6%)。结论新生儿高胆红素血症病因多且复杂,应加强对新生儿高胆红素血症的病因诊断,做到早预防,早诊断,早治疗,尽可能减少新生儿高胆红素血症的发生。
Objective To investigate the common causes of neonatal hyperbilirubinemia,to improve its diagnosis and treatment level,to reduce the rate of missed diagnosis,misdiagnosis rate,disability rateand death rate.Methods The selection in our hospital from 2011February -2013 year in March admitted 195 cases ofhyperbilirubinemia of newborn,on a variety of common causes were analyzed retrospectively. Results neonatal hyperbilirubinemiacaused by many reasons,the main reason is:the common infection in 52 cases (26.7%),perinatal factors in 44 cases (22.6%),ABO hemolytic disease in 33 cases (16.9%),glucose-6-phosphate dehydrogenase (G6-PD) deficiency in 23 cases (11.8%),20 cases of thalassemia (10.3%),breast milk jaundice in 18 cases (9.2%),5 cases with unknown causes (2.6%).Conclusion The causes of neonatal hyperbilirubinemia and complex,should strengthen the etiological diagnosis of neonatal hyperbilirubinemia,early prevention,early diagnosis,early treatment,as far as possible,reduce the

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目的讨论骨髓细胞学检查在贫血病因诊断中的临床价值。方法对168例贫血患者,使用瑞氏染色法进行骨髓细胞学检验。首先,使用常规血液检查,做成瑞氏染色涂片;然后,在严格的无菌条件下进行骨髓穿刺,进行骨髓细胞学检验。结果168例患者中的130(77.4%)例确诊病因。结论骨髓细胞学检验对贫血病因的确定有十分重要的临床意义。
10.3969/j.issn.1671-3141.2013.04.025

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目的回顾性地分析老年心力衰竭住院病例的病因变迁,探讨老年心力衰竭的防治对策。方法从住院病历数据库中检索出1993年1月至2010年12月首次因心力衰竭住院的老年患者6288例,以6年为时间段分成A,B和C组,分析比较3组不同性别、年龄患者病因学和住院30d病死率的变迁。结果(1)18年间住院患者数逐年增多,性别构成方面男性下降,女性上升;年龄构成方面60~69岁下降,≥80岁上升。(2)高血压病和糖尿病比例增多;冠心病、陈旧性心肌梗死和肺心病比例下降;急性心肌梗死、风湿性心脏病、先天性心脏病、贫血和甲亢性心脏病无显著性变化。(3)诱因中肺炎、房颤的比例上升,室性心动过速/心室颤动的比例下降。(4)两种病因、3种及3种以上病因的比例随年龄增高而上升,但3个时间段间差异无统计学意义。(5)18年间住院30d病死率逐渐降低,男性中下降更明显。结论18年间,老年心力衰竭首次住院患者的病因、诱因或伴随疾病构成比中,高血压病和糖尿病增多,冠心病、肺心病比例下降;肺炎、房颤比例上升;住院期病死率下降,其原因值得深入研究。
Objective To analyze the etiological changes in the elderly hospitalized patients with heart failure (HF) and investigate the strategies to prevent and treat HF. Methods A retrospective study was performed on 6 288 patients (4001 males and 2287 females) with a primary diagnosis of validated HF who were consecutively admitted to our hospital during the years of 1993 to 2010. The patients were divided into groups A, B and C with 6 years as interval. The etiological features and 30-day in-hospital mortality were compared in different genders and ages from the above 3 groups. Results During the period of 18 years, the number of the inpatients was increased year by year, with the proportion of women increased and men decreased, and the percentage of age 60 to 69 years old declined and over 80 years old risen. Of the 6288 patients, the proportion of accompanied hypertension and diabetes was increased, but that with coronary artery diseases, prior myocardial infarction and cor pulmo

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目的:探讨血液学初筛指标阳性且临床常规基因检测阴性的疑似地中海贫血(简称地贫)患者再进一步行常规和罕见基因突变检测,丰富对地贫的病因学认识。方法以深圳市儿童医院地贫血液学初筛[ Hb、RBC 平均容积(MCV)、RBC 平均 Hb 量(MCH)、Hb 电泳)]试验阳性,且常规基因(3种缺失型地贫、3种非缺失型α地贫、17种β地贫点突变)检测阴性的疑似地贫的连续病例为研究对象,提取全血基因组 DNA,以 Sangre 基因测序、Gap-PCR 和荧光定量 PCR的方法,检测常规基因和罕见基因突变情况。结果2011年1~9月地贫血液学初筛阳性且常规基因检测阴性285例患者进入本文分析,其中﹤16岁279例。进一步基因检测阳性21例(7.4%):①常规基因检测阳性5例(1.8%),CD27-28(+ C)、CD41-42(- TCTT)各2例,IVS -2-654(C ﹥ T)1例;②罕见基因检测阳性16例(5.6%),其中 Sangre 基因测序检出:异常 Hb 病3例(Hb Poet Phillip、Hb Eenz、Hb J-Bangkok 各1例),Hb Eenz 类型为亚洲人群中首次检出;非缺失型β地贫-90(C ﹥ T)2例;Gap-PCR 和荧光实时 PCR 检出:缺失型α地贫5例(-α/αα2例、--/αα3例),缺失型β地贫(-/β)3例,α地贫合并β地贫(--/αα合并-/β)1
Objective To invrstigatr globin grnrs of susprctrd thalrssrmia patirnts whosr scerrning indicatoes wrer positivr and ergulae grnr drtrction wrer nrgativr,and to rxploer novrl typrs of grnr mutation. Methods Consrcutivr patirnts with positivr blood scerrning(Hb,MCV,MCH and HbA2,HbF)and nrgativr ergulae grnr drtrction(3 typrs of drlrtrd α-thalrssrmia,3 typrs of nondrlrtrd α-thalrssrmia,17 typrs of nondrlrtrd β-thalrssrmia)wrer rneollrd at Shrnzhrn Childern''s Hospital. Wholr blood grnomic DNAs wrer rxteactrd and srnt foe fuethre ergulae grnr and eaer grnr drtrction in Sangre srqurncr,Gap-PCR and eral-timr PCR. Results 285 patirnts collrctrd feom Jan. to Srp. 2011 wrer erceuitrd,21 casrs with grnrtic abnoemality wrer obsrevrd (accounting foe 7. 4% ). ①5 casrs(1. 8% )wrer positivr foe ergulae grnr drtrction,including CD27 - 28( + C)(2 casrs)、CD41- 42( - TCTT)(2 casrs),IVS - 2 - 654(C ﹥ T)(1 casr). ② Raer grnr drtrction was positivr in 16 casrs(5. 6% ). Onr casr of Hb Eenz

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目的:了解起病与妊娠相关的肾脏病女性患者的发病率、病因及一般情况。方法:收集2004年8月~2013年1月肾脏科,于妊娠期间及产后6个月内诊断为肾脏病的女性患者,并记录其临床资料。结果:起病与妊娠相关的肾脏病女性的发病率为1.49%(43/2891),53.4%为CKD1~2期患者,6名女性进入终末期肾脏病(0.208%)。67.4%在妊娠期间诊断为肾脏病,大部分因蛋白尿发现(46.5%)。最多的临床诊断为慢性肾小球肾炎(27.9%),最多的病理诊断为IgA肾病(50%)。平均血红蛋白浓度为(105±30)g/L,血钙磷代谢异常比例为20.9%。妊娠至诊断肾脏病的平均时间为(128±288)周(中位数25周),她们的剖宫产比例及死产比例均高于健康妊娠女性(53.8%比16.7%,60%比0%,P<0.05)。43名中的8名女性接受肾脏替代治疗。结论:起病与妊娠相关的肾脏病女性患者的发病率高于文献报道,这些女性的临床及病理诊断与我国慢性肾脏病的流行病学一致,他们贫血及钙磷代谢的控制情况不理想。
Objective:To learn the incidence,causes and general condition of women whose kidney disease onset related to pregnancy. Methods:Women of Han ethnics whose kidney disease onset related to pregnancy were collected from August 2004 to Jan-uary 2013 in nephrology department Inclusive criteria was women diagnosed with kidney disease during pregnancy or within six -month after delivery. Clinical data were recorded. Results:The incidence of women whose kidney disease onset related to pregnancy is 1. 49%(43/2 891). 53. 4% women in chronic kidney disease stage 1 ~2. Six women proceeded to end stage renal disease (0. 208%). Most were discovered during pregnancy(67. 4%),for discovering proteinuria(46. 5%). The most clinical diagnosis was chronic glomerularnephritis(27. 9%). The most pathological diagnosis was IgA nephropathy(50%). Mean hemoglobin was (105 ± 30)g/L. Percentage of calcium and phosphorus abnormalities was 20. 9%. Average week from gravidity till kidney disease di-agnosis

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