目的建立氯达软膏、利唑软膏、硫磺软膏医院软膏剂微生物限度检查方法。方法按《中国药典》2010年版二部微生物限度检查法中对细菌、霉菌及酵母菌计数方法和控制菌检查法进行验证。结果氯达软膏和利唑软膏细菌、霉菌及酵母菌计数检查采用薄膜过滤法,控制菌检查均采用薄膜过滤法;硫磺软膏细菌、霉菌及酵母菌计数检查采用培养基稀释法,控制菌金黄色葡萄球菌检查采用培养基稀释法,铜绿假单胞菌检查采用常规法。结论医院软膏制剂必须通过方法验证试验建立合理的检验方法,以保证检验结果的准确性。

Objective To establish the methodological validation for microbial limit tests hospital ointment preparations, such as chlorine ointment, azole ointment and sulfur ointment. Methods According to the microbial limit test in 2010 edition of China Pharmacopoeia, this paper setted the methodological validation for the counting methods of bacteria, mold and yeast and the controlling bacteria checking methods. Results Membrane filtration method could be used in the counting test of bacteria mold and yeast for chlorine ointment and azole ointment, and also this method was used in the controlling bacteria checking. For the sulfur ointment, media dilution method could be used in the counting test of bacteria mold and yeast, and also this method was used in the controlling bacteria checking of staphylococcus aureus, and the routine method was used in the pseudomonas aeruginosa checking. Conclusion To ensure the accuracy of test results, it must be established checking methods for the hospital oi

目的观察复方丙酸氯倍他索软膏与他卡西醇软膏联合治疗寻常型银屑病的疗效。方法将112例寻常型银屑病患者按照随机数字法分为研究组和对照组。对照组给予复方丙酸氯倍他索软膏,研究组给予复方丙酸氯倍他索软膏及他卡西醇软膏联合治疗,观察两组的临床治疗效果。结果研究组有效率为91.1%,明显高于对照组71.4%,差异有统计学意义(P0.05)。结论复方丙酸氯倍他索软膏与他卡西醇软膏联合治疗寻常型银屑病效果显著,能有效改善患者临床症状,不良反应少,安全性高,值得临床应用。

Objective To investigate the effect of compound clobetasol propionate ointment combined with tacalcitol ointment on treating psoriasis vulgaris.Methods 1 12 patients with psoriasis vulgaris were divided randomly into experiment group and control group. The patients in the experiment group were embrocated with compound clobetasol propionate ointment combined with tacalcitol ointment,while the control group only with compound clobetasol propionate ointment.The clinical efficacy of both groups was observed and recorded.Results The effective rate of the experiment group (9 1.1%)was much higher than the control group (7 1.4%),and the difference was statistically significant (P 0.05 ).Conclusion Compound clobetasol propionate ointment combined with tacalcitol ointment is farely safe and effective in treating psoriasis vulgaris and improving clinical symptoms,with less side effects for clinical application.

探讨龙珠软膏对肛肠疾病术后创面愈合的治疗效果。方法:选择肛肠病手术患者610例,将龙珠软膏均匀涂抹覆盖在痔、肛裂、肛周脓肿、肛瘘术后创面上,或将龙珠软膏纱条塞入肛内,对患者用药前后创面愈合状况、症状及体征进行比较。结果:龙珠软膏促进痔疮、肛周脓肿、肛瘘术后创面愈合,显效率分别为98.5%、98%、97.6%。结论:龙珠软膏能有效地促进肛肠病术后创面愈合。

Objective:To explore the therapeutic effect of Long Zhu ointment on wound healing after anorectal surgery.Methods:610 cases of anorectal surgery were selected.We evenly covered the postoperative wound of the hemorrhoids,anal fissure,perianal abscess,anal fistula with Long Zhu ointment,or took Long Zhu ointment gauze into the anus.We compared the wound healing situation,symptoms and syndromes of patients before and after the treatment.Results:Long Zhu ointment can promote the wound healing of hemorrhoids,perianal abscess,anal fissure after the operation.The rate of significant efficiency were 98.5%,98%,97.6%respectively.Conclusion:Long Zhu ointment can promote wound healing after anorectal postoperative.

京万红软膏是一种治疗烧伤及烫伤的常用药。因其组方独具特色，疗效确切，其临床主治病症范围不断扩大。本文总结了近十年京万红软膏的临床应用情况，为京万红软膏的合理用药和二次开发提供有意义参考。

Jingwanhong Ointment is a kind of effective medicine for treating burn and scald. Because of its unique com-posing formula and the affirmed therapeutic effect,the main indications spectrum were expanded. This article reviewed the clinical research on Jingwanhong Ointment in recent years. It provided the foundation for the available application and the further study.

目的：介绍本院自制消肿止痛膏的制备方法及质量标准，并对其临床疗效进行观察评价。方法采用普通传统工艺制备软膏，并对其临床疗效与普通狗皮膏进行对比观察。结果该软膏制备方法可行，且在应用过程中未出现明显不良反应；临床疗效消肿止痛软膏痊愈率为69.0%；对照组为52.4%，治疗组明显优于对照组( P<0.05)。结论消肿止痛软膏制备方法安全可靠；治疗软组织损伤效果明显，适合临床推广应用。

Objective To introduce the self-made Xiaozhong Zhitong ointment preparation method and quality standard, and the clinical curative effect evaluation. Methods the general traditional process preparation ointment, and to compare the clinical curative effect and the ordinary plaster. Results the ointment preparation method is feasible, and no obvious adverse reactions appear in the application process; Xiaozhong Zhitong ointment clinical cure rate was 69%; the control group was 52.4%, significantly better than the control group (P<0.05). Conclusion: Xiaozhong Zhitong ointment preparation method is safe and reliable; the treatment effect of soft tissue injury obviously, suitable for clinical application.