为评价黄枙子的食用安全性,以提高黄枙子的综合开发利用,本研究对黄枙子中枙子黄色素和重金属的含量分别进行了测量.将黄枙子光波消煮,用紫外分光光度计测定其矿物质和枙子黄色素的含量,测试结果显示黄枙子中的矿物质和枙子黄色素含量丰富.本研究以砷为研究对象,进行急性经口毒性、大鼠精子畸形、大鼠骨髓细胞微核、180天喂养等安全性毒理学评价试验研究.试验结果表明：所测定的40批黄枙子样品中,其水溶出物中的砷、汞、镉含量分别为：w（汞）≤0.0153 ug/g、w（砷）≤0.0613 ug/g,w（镉）≤0.0167 ug/g,均极其微小;遗传毒性试验结果无显著相关性,180天喂养试验结果表明,在本试验剂量范围内无毒副作用.研究结果显示：黄枙子中的枙子黄色素含量丰富,且具有较好的食用安全性.

In order to evaluate edible safety of Yellow Ezi and improve its comprehensive utilization, this study determined respectively the content of gardenia yellow pigment and Heavy Metals in Yellow Ezi. By digestion of the yellow Ezi light, the content of minerals and gardenia yellow pigment were deter-mined by UV spectrophotometry. The results showed that the content of minerals and gardenia yellow pig-ment in Yellow Ezi was rich. Arsenic as the object of study, the experimental study was carried out to e-valuate the acute oral toxicity, rat, micronucleus, sperm deformity of bone marrow cells of rat in 180 days feeding safety toxicology. The results showed that in the determination of the 40 batch of Yellow Ezi sam-ples, arsenic, mercury compounds, cadmium content were dissolved in water:w ( arsenic) ≤0. 061 3 ug/g, w (mercury) ≤0. 015 3 ug/g, w (CD) ≤0. 016 7 ug/g, which were extremely small. Genetic toxicity tests showed no significant correlation, 180 days feeding test resu

清代著名藏书家黄丕烈的藏书题跋于版本学、目录学等方面有很大价值,清潘祖荫、缪荃孙等人都曾搜集黄丕烈的藏书题跋,编纂成书。通过对部分黄氏手书题跋与诸家辑本的校勘,可发现后人在转抄过程中出现的讹、脱、倒、衍等问题,其中不少异文涉及是非问题。在诸家辑本基础上对黄氏藏书题跋的重新纂集校录,可为广大读者提供一个更为完整精善的本子。

The famous bibliophile Huang Pilie wrote many books inscriptions in the Qing Dynasty. These inscriptions are of great value for the study of editions and bibliography. People like Pan Zuyin and Miao Quansun collected Huang''s inscriptions and compiled them into books. While collating Huang''s handwritten inscriptions and some of the collections by others, I have found that there are all kinds of errors. Therefore, based on the collected inscriptions, we may as well come up with a new version for readers.

本研究旨在探讨饲粮中添加不同水平大豆异黄酮（ISO）对固始鸡小肠形态结构的影响。将80只1日龄固始鸡雏鸡随机分成4组：对照组（饲喂基础饲粮）、3 mg/kg大豆异黄酮组、6 mg/kg大豆异黄酮组、9 mg/kg大豆异黄酮组,每组20只鸡。结果表明：1）大豆异黄酮对固始鸡体重和小肠长度没有显著影响（P〉0.05）;2）大豆异黄酮显著影响了空肠和回肠绒毛高度、隐窝深度和绒毛高度/隐窝深度（V/C）值（P〈0.05）;3）大豆异黄酮对固始鸡35日龄十二指肠和21、35日龄回肠杯状细胞的数量具有显著影响（P〈0.05）;4）除35日龄空肠外,大豆异黄酮对固始鸡肠道肥大细胞的数量具有显著影响（P〈0.05）。综上,在本试验条件下,固始鸡饲粮大豆异黄酮的最适添加水平为6 mg/kg。

This study was conducted to investigate the effects of different adding levels of soybean isoflavones ( ISO) on the morphological structure of the small intestinal of Gushi chickens. Eighty 1-day-old Gushi chick-ens were randomly divided into four groups ( with 20 chickens per group) as control group ( feeding with basal diet) , 3 mg/kg ISO group, 6 mg/kg ISO group and 9 mg/kg ISO group. The results showed as follows:1) ISO had no significant effect on body weight and length of the small intestine of Gushi chickens ( P>0.05) . 2) ISO had significantly effect on villus height, crypt depth and the ratio of villus height to crypt depth of jejunum and ileum ( P<0.05) . 3) ISO had significantly effect on the number of goblet cells of duodenum at 35 days of age and ileum at 21 and 35 days of age ( P<0.05) . 4) Expected jejunum at 35 days of age, ISO had signifi-cantly effect on the number of mast cells of small intestine ( P<0.05) . The results indicate that 6 mg/kg is the optimal

本试验对桑叶总黄酮的提取条件进行了研究，并利用AB-8大孔树脂对粗提黄酮进行初步纯化。结果表明：最佳提取条件为时间3 h、温度80℃、乙醇浓度60%、料液比1∶30（g/mL），此时，大孔树脂AB-8可以有效富集与纯化桑叶黄酮。

In this study,different extraction conditions of flavonoid in mulberry leaves were investigated.Flavonoids were extracted by alcohol and purified by AB-8 macroporous resin.The results showed that the optimal extraction time was 3 h,the optimal temperature was 80 ℃,the optimal alcohol concentration was 60%,and the optimal extraction solid-liq-uid ratio was 1∶30(g/mL).AB-8 macroporous resin could effectively enrich and purify macroporous of flavonoids from the mulberry leaves in above condition.

目的：优化热水浸提黄芩茎叶中总黄酮的提取工艺。方法选取浸提时间、水温、料液比为影响因素,在单因素试验结果的基础上确定各因素的分析水平,利用响应面中心组合法设计试验方案。结果以总黄酮提取量为响应值,建立了数学模型并得到黄芩茎叶中总黄酮提取工艺的优化组合为：浸提时间70 min、水温89℃、料液比1：55,并分析了双因素间的交互作用。结论本研究所提出的优化组合可以为黄芩茎叶总黄酮的提取工艺提供一定理论指导。

Objective To optimize the extraction of total flavonoids from stems and leaves of Scutellaria by hot water immersion method. Methods The extracting time, temperature and ratio of water were chosen as influencing factors, and based on results of single factor experiments, the analytical levels of these 3 factors were established. Experimental scheme was designed by central composite of response surface methodology. Results Taking extraction ratio of flavonoids as response, a mathematics model was established. The opti-mum scheme of extraction technology for rein was obtained, including extraction temperature 89℃, extraction time 70 min, and material-water ratio 1:55 (mL/g). In addition, the interaction analysis between 2 factors was analyzed. Conclusion This research provided a certain theoretical instrument and application value for the extraction of flavonoids in Scutellaria baicalensis.