异羟肟酸及其衍生物是广泛存在于玉米等禾本科作物中的一种广谱抗性物质，丁布（DIM-BOA）是玉米植株中含量最大的异羟肟酸。为了明确不同丁布含量的玉米品种对亚洲玉米螟危害和生长发育的影响，采用高效液相色谱法测定了11个玉米品种五叶期的丁布含量；室内条件下在玉米叶片上人工接虫，调查亚洲玉米螟在11个玉米品种上的危害程度；用丁布含量依次降低的登海662、浚单20、隆玉602品种（P＜0.05）叶片饲喂亚洲玉米螟初孵幼虫，探讨不同含量丁布胁迫下亚洲玉米螟生长发育的变化。结果表明，不同玉米品种间丁布含量差异显著，登海662含量最高，德单5号含量最低。接种亚洲玉米螟后，丁布含量较低的德单5号、隆玉602、新单36、金骆驼335品种的花叶指数均大于40％，随着玉米品种丁布含量的增加，玉米螟的危害程度逐渐减轻。亚洲玉米螟幼虫发育历期和幼虫＋蛹总历期在取食3个玉米品种处理之间具有差异，其中取食隆玉602的幼虫发育历期和总发育历期最短，取食浚单20的处理最长。取食3个玉米品种的亚洲玉米螟均不能正常交配产卵和完成世代周期，其化蛹率、蛹质量和羽化率均随玉米品种丁布含量的降低而升高。

Hydroxamic acid and its derivatives,widely existing in gramineous crops such as maize,are a group of compounds with a broad spectrum of biological activities.DIMBOA(2 ,4-dihydroxy-7-methoxy-1 ,4-benzoxazin-3-one)is the dominant hydroxamic acid in maize.In the present study,high performance liquid chromatography(HPLC)was applied to qualitatively analyse the content of DIMBOA in 1 1 maize varieties;In the indoor test condition,newly hatched larvae of Ostrinia furnacalis were put on the maize leaves artificially,and the damaged degree of 1 1 maize varieties was investigated after several days;In order to investigate the changes in the growth of O.furnacalis under different degree of DIMBOA stress, Denghai 662,Xundan 20,Longyu 602 maize varieties with different levels of DIMBOA were applied to rear newly-hatched larvae.The results revealed that there was significant difference in DIMBOA content of different maize varieties,the DIMBOA content of Denghai 6 6 2 was the highest,and t

目的：系统评价布地奈德联合沙丁胺醇雾化吸入治疗哮喘的疗效。方法根据Cochrane系统评价的要求，全面检索万方数据库、CNKI数据库、维普中文科技期刊全文数据库及Pubmed数据库，采用RevMan4．3软件，对符合纳入标准的51篇文献，共计4649例哮喘患者进行Meta分析。结果以总有效率为指标，常规治疗基础上联合雾化吸入布里奈德及沙丁胺醇（联合治疗组）疗效与采用抗感染、支气管扩张药物、吸氧等常规治疗（常规治疗组）（RR＝1．27，95％CI：1．23～1．32）以及常规治疗基础上雾化吸入布里奈德（布地奈德组）（RR＝1．31，95％CI：1．16～1．49）和常规治疗基础上雾化吸入沙丁胺醇（沙丁胺醇组）（RR＝1．23，95％CI：1．17～1．28）相比更高，且差异有统计学意义（P＜0．01）；以住院率为指标，联合治疗组与沙丁胺醇组（RR＝0．34，95％CI：0．13～0．90）相比更低，且差异有统计学意义（P＜0．05）。结论布地奈德联合沙丁胺醇雾化吸入治疗哮喘疗效明显。

Objective To assess the efficacy of nebulized budesonide and salbutamol in the treatment of asthma by Meta‐analy‐sis .Methods According to the requirements of Cochrane systematic review ,a through literature search was performed among Wan‐fang database ,CNKI database ,VIP database of Chinese Periodicals and Pubmed database .Meta‐analysis was conducted on a total of 4 649 patients involved in 51 papers that met the inclusion criteria by RevMan4 .3 software .Results Compared with control group (RR=1 .27 ,95% CI=1 .23-1 .32) ,budesonide group which was treated by atomization inhales of nebulized budesonide based on routine treatment(RR=1 .31 ,95% CI=1 .16-1 .49) and salbutamol group which was treated by atomization inhales of salbutamol based on routine treatment(RR=1 .23 ,95% CI= 1 .17 -1 .28) ,the combined group which was treated by atomization inhales of nebulized budesonide and salbutamol based on routine treatment exhibited higher rates of total effectiveness with signi

目的：探讨布地奈德联合沙丁胺醇雾化吸入治疗支气管哮喘急性发作的临床疗效。方法选取88例支气管哮喘急性发作患者，分为观察组与对照组，各44例，分别给予布地奈德联合沙丁胺醇雾化吸入治疗、沙丁胺醇雾化吸入治疗，比较两组临床疗效及肺功能指标。结果治疗后，观察组与对照组患者总有效率比较（90.9%对79.5%），差异有统计学意义（P＜0.05）；与治疗前比较，两组患者治疗后肺功能指标明显升高（P＜0.05），且观察组明显优于对照组（P＜0.05）。结论布地奈德联合沙丁胺醇雾化吸入在治疗支气管哮喘急性发作中具有重要作用。

Objective To investigate the clinical effect of budesonide combined with salbutamol atomization inhalation in treatment of acute attack of bronchial asthma.Methods Selected 88 cases of acute attack of bronchial asthma patients,divided into the observation group and control group,each 44 cases,were given budesonide combined with salbutamol atomization inhalation treatment,salbutamol atomization inhalation treatment,compared two groups of clinical curative effect and lung function index.Results After treatment,two groups of patients with total efective rate(90.9%vs79.5%),the diference was statisticaly significant(P<0.05);compared with before treatment, pulmonary function index increased significantly in the two groups after treatment(P<0.05),patients in observation group were significantly better than the control group (P<0.05).Conclusion Joint salbutamol aerosol inhalation budesonide in treating bronchial asthma with acute plays an important role.

目的：探讨沙丁胺醇联合布地奈德治疗小儿哮喘急性发作的临床效果及对肺功能的影响。方法将80例支气管哮喘患儿按照就诊顺序分为两组，各40例。对照组采用沙丁胺醇治疗，观察组采用沙丁胺醇联合布地奈德治疗，对比两组临床治疗效果及肺功能改善情况。结果观察组治疗总有效率高于对照组（ P ＜0．05）；治疗后观察组最高呼气流速变异率（PEER）、肺活量（VC）、用力肺活量（FVC）、第1秒用力呼气量（FEV1）均大于对照组（ P ＜0．01）。结论沙丁胺醇联合布地奈德治疗小儿哮喘急性发作效果确切，可提高治疗有效率，且在肺功能改善方面也具有显著效果。

Objective To investigate the clinical efficacy of salbutamol and budesonide in treatment of children with acute asth -ma and effects on the lung function .Methods Eighty children with bronchial asthma were randomly divided into two groups ,40 cases in each group, according to the sequence of admission to hospital .The study group was treated with budesonide and salbutamol Ned ,while the control group undertook albuterol therapy only .We compared the treatment efficiency and the total degree of change in lung functions . Results The total effective rate of the study group was higher than that of control group ( P <0.05).PEER,VC,FVC,FEV1 of the study group after treatment were higher than that of the control group , with significant difference ( P <0.01).Conclusion Salbutamol and budesonide in treatment of children with acute asthma has better clinical efficacy , and can significantly improve the lung function .

目的：分析布地奈德与沙丁胺醇雾化吸入治疗支气管哮喘急性发作的临床疗效。方法：回顾性分析2012年6月～2013年6月期间在我院治疗的64例支气管哮喘急性发作患者的临床资料。将64例患者随机分为治疗组和对照组各32例，治疗组给予布地奈德与沙丁胺醇联合雾化吸入治疗，对照组仅给予沙丁胺醇雾化吸入治疗，观察两组临床疗效及不良反应。结果：治疗组总有效率为96．88％，对照组总有效率为84．37％，两组差异有统计学意义（P＜0．05）；治疗组FEV1、FVC和PEF均显著高于对照组（P＜0．05）。结论：布地奈德与沙丁胺醇雾化吸入治疗支气管哮喘急性发作疗效显著，安全性好，值得临床推广应用。

Objective:To observe the clinical ef ects of joint aerosol inhalation of budesonide and salbutamol for acute at ack of bronchial asthma.Methods:A retrospective a-nalysis of clinical data was conducted in 64 patients with acute at ack of bronchial asthma who were admit ed in our hospital from June 2012 to June 2013,and they were randomly di-vided into treatment group and control group,each group contained 32 cases.The treatment group were treated with aerosol inhalation of budesonide and salbutamol,the control group were treated with salbutamol.The curative ef ects were compared between the two groups after treatment.Results:The total ef ective rate in the treatment group was 96.88%,the total efective rate in the control group was 84.37%,it significantly higher than control group(P<0.05).The FEV1,FVC,and PEF of treatment group was significantly higher than those of control group(P<0.05).Conclusion:Joint aerosol inhalation of budesonide and salbutamol for acute at ack of bronchial asthma