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双语推荐:乌梢蛇

王莒生教授从事中医临床工作30余年,治病广泛,思路开阔,用药风格独特,治疗用药胆大心细,疗效明显。本文介绍王老临床中巧用及活用芍药、竹茹、威灵仙及乌梢蛇四味中药,给临床人员及研究者以启迪和指导。
Professor W ang Jusheng has practiced traditional Chinese medicine (TCM) for more than 30 years. She has experiences in the treatment of various diseases with an open mind and unique medication style. Her medication selection is bold but cautious with obvious curative effect. This article introduced the flexible clinical application of four TCM herbs, which are peony, bamboo shavings, clematis root and zaocys dhumnades in order to provide inspira-tion and guidance for TCM clinical practitioners and researchers.

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对中药材蛇蜕及其易混伪品进行分子鉴定,以确保该中药材的临床用药安全。方法:以COI序列作为DNA条形码,对蛇蜕原药材进行DNA提取,PCR扩增和序列测定,对13个物种的68份样品进行DNA Barcoding Gap分析和系统聚类分析。结果:蛇蜕3种基原黑眉锦蛇Elaphe taeniura Cope、锦蛇Elaphe carinata(Guenther)和乌梢蛇Zaocys dhumnades(Cantor)具有DNA Barcoding Gap,在邻接(NJ)系统聚类树上分别聚为独立一枝。结论:COI作为DNA条形码,不仅可以鉴定中药材蛇蜕的3种基原,而且可以区分蛇蜕及其易混伪品,表明DNA条形码可以用于中药材蛇蜕的鉴定。
Objective: This study aimed to distinguish Serpentis Periostracum from its adulterants, which will provide the basis for its safe application. Methods: Here, COI sequences of 68 samples from 13 species were PCR amplified and sequenced. Furthermore, the DNA Barcoding Gap and phylogenetic cluster analysis were carried out. Results:The results exhibited that the COI sequences of all the three origin animals of Serpentis Periostracum have DNA Barcoding Gap. For phylogenetic cluster analysis, all the three origin animals showed monophyletic and every species can be discriminated clearly. Conclusion: COI is an effective DNA barcode for the identification of Serpen-tis Periostracum.

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观察六味地黄汤加味联合盐酸左西替利嗪片治疗老年糖尿病皮肤瘙痒症的疗效和安全性。方法:66例老年糖尿病皮肤瘙痒症患者随机分治疗组和对照组,各33例。治疗组采用六味地黄汤加味(熟地黄、山萸肉、山药、丹皮、泽泻、茯苓、蝉蜕、僵蚕、乌梢蛇)联合盐酸左西替利嗪片治疗;对照组单纯采用盐酸左西替利嗪片治疗。结果:治疗组有效率为84.84%,对照组有效率为63.63%,二者差异有统计学意义(P0.05);治疗组不良反应6.06%,对照组不良反应15.15%(P0.05),二者差异无统计学意义。结论:六味地黄汤加味联合盐酸左西替利嗪片治疗老年糖尿病皮肤瘙痒症安全有效。
Objective: To observe the efficacy and safety of the Liuwei Dihuang decoction combined with levocetirizine hydrochloride tablets in the treatment of elderly diabetic pruritus. Methods:66 cases of elderly diabetic pruritus were randomly divided into treated group and control group, 33 cases each. The treated group using the Liuwei Dihuang decoction (Shudihuang, Shanyurou, Shanyao, Danpi, Zexie, Fuling, Chantui, Jiangcan, Wushaoshe) combined with levocetirizine hydrochloride tablets in the treatment; The control group using levocetirizine hydrochloride tablets. Results:The efficiency of the treated group was 84.84%and the control group 63.63%, thedifference was statistically significant (P 0.05). Conclusion: Using Liuwei Dihuang decoction and levocetirizine hydrochloride tablets to treat elderly diabetic pruritus is a safe and effective therapy.