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双语推荐：右心室容积

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目的 应用单心动周期实时三维超声心动图评价房间隔缺损(ASD)右心室形态及功能.方法 选取34例健康志愿者(对照组)和27例接受介入治疗的房间隔缺损患者(ASD组),对所有研究对象进行单心动周期实时三维超声心动图检查,分别测量右室舒张末容积(IEDVRV)、右室收缩末容积(IESVRV)、右室每搏量(ISVRV)、右室射血分数(RVEF),同时对ASD患者通过三尖瓣反流估测肺动脉收缩压(PASP)与心导管测得平均肺动脉收缩压(PAMP),两者分别与三维右心室舒张及收缩末容积进行相关性研究.结果 ASD组三维右心室舒张末容积(IEDVRv)、三维右心室收缩末容积(IESVRv)、三维右心室每搏输出量(ISVRV)及三维右室射血分数(RVEF)均大于对照组(P＜0.05),ASD组单心动周期三维右室容积随时间变化幅度较对照组低,两组均在心动周期40％处出现最大变化值,且三维右心室形态相关参数(IEDVRV、IESVRv)与右心导管所测平均肺动脉压力(PAMP)及通过三尖瓣反流测得肺动脉收缩压(PASP)呈正相关.结论 单心动周期实时三维超声能够更准确、快速地反映ASD患者右心室形态及功能的改变,通过右室容积的变化可以无创地间接判断出肺动脉压力的高低.
Objective To investigate the right ventricular morphology and function of patients with atrial septal defects by single beat real-time three-dimensional echocardiography.Methods Thirty-four healthy volunteers and twenty-seven ASD patients were enrolled consecutively as normal controls and the ASD group respectively.Single cardiac cycle real-time three dimensional echocardiography was performed in all to evaluate parameters concerning modality and systolic function of participants'' right ventricle.The relationship of indexed right ventricular end diastolic volume (IEDVRV) and end systolic volume(IESVRV)with mean pulmonary arterial pressure measured through cardiac catheter and systolic pulmonary artery pressure calculated though the three tricuspid regurgitation were observed.Results Indexed right ventricular end diastolic volume (IEDVRv),end systolic volume(IESVRV),right ventricular stroke volume (ISVRV) and right ventrieular ejection fraction (RVEF) were greater in the ASD group than

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目的：评价ASD患者术前及术后不同时间右心室容量及收缩功能。方法使用实时三维超声心动图（RT-3DE）对30例单纯继发孔型房间隔缺损患者术前及术后不同时期（7 d至6个月）测量右心室舒张末期容积（RVEDV）、收缩末期容积（RVESV）、右心室射血分数（RVEF），对比上述参数分析右心室收缩功能。结果术后7 d右心室RVEDV、RVESV略降低、RVEF略升高，但与术前无显著差异（ P＞0.05），术后3～6个月，RVEDV、RVESV及RVEF较术前明显增高（ P＜0.01）。结论 RT-3 DE可较好评价继发孔型房间隔缺损患者手术后右心室收缩功能。
Objective To evaluate right ventricular ( RV) morphology and systolic function before and after different times in the patients with atrial septal defect ( ASD) by real-time three dimensional echocardiography ( RT-3DE).Methods RT-3DE was applied to measure right ventricular end diatolic volume (RVEDV),end systolic volume(RVESV)and ejection fraction(RVEF)before and after operation,7 d,1 month,3 months and 6 months, these parameters were compared to analyse right ventricular systolic function .Results RVEDV,RVESV and RVEF decreased slightly 7 d after operation ,and RVEF increased slightly too ,while those showed no significant difference ( P>0.05 ) .RVEDV and RVESV decreased obviously , while RVEF increased significantly from 3 months to 6 months after operation ( P<0.01 ) .Conclusions Real-time dimensional could be better estimated right ventricular systolic function of ASD patients after operation .

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目的 评价超声心动图多种方法测量右心室容积的准确性.方法 46例健康志愿者,男30例,女16例,年龄18～59岁,平均(34±14)岁,在24 h内进行常规二维超声心动图(2-DE)、实时三维超声心动图(RT-3DE)及心脏磁共振(cMRI)检查.2-DE计算右心室容积采用Simpson法、对切半椭圆体法和双平面面积-长度法进行.RT-3DE图像分别采用三平面成像法及TomTec 4D RV-Function CAP软件进行右室容积计算.cMRI图像采用Argus软件计算右室容积.右室容积分别测量右室舒张末期容积(RVEDV)和右室收缩末期容积(RVESV).将超声测量结果与cMRI结果进行对比研究,两种方法的一致性评价采用Bland-Altman分析.结果 ①与cMRI相比较,Simpson法、对切半椭圆体法及三平面法所测右室容积低估,差异有统计学意义(P＜0.05);双平面面积-长度法及TomTec 4D RV-Function CAP所测右室容积差异无统计学意义(P＞0.05);②相关分析表明,Simpson法及三平面法与cMRI测值相关性较差(r=0.3～0.4).TomTec 4D RV-Function CAP、对切半椭圆体法及双平面-面积长度法右心室容积测值均与cMRI右心室容积测值高度相关(r=0.7～0.8,P＜0.001).③超声测值与cMRI测值进行Bland-Altman分析显示,TomTec法及双平面面积-长度法与cMRI的右室容积测值
Objective To evaluate the accuracy of methods in echocardiographic measurements of right ventricular (RV) volume.Methods Forty-six healthy volunteers were examined by two dimensional echocardiography (2-DE),real time three-dimensional echocardiography (RT-3DE) and cardiac magnetic resonance imaging (cMRI) within 24 hours.2 DE adopts three methods to measure RV volume,the first is Simpson,the second is the half ellipsoid method,and the last is biplane area-length method.In RT 3DE,RV volume were calculated respectively by tri-plane method and TomTec 4D RV-function CAP software.In cMRI,RV volume was calculated by Argus software.Right ventricular end diastolic and end-systolic volume (RVEDV,RVESV) were measured respectively.Then the echo measurement were compared to cMRI.Consistency of two methods was evaluated by Bland-Altman analysis.Results ①As compared to cMRI,Simpson,the half ellipsoid method and tri-plane method underestimated RV volume,with statistical significance(P ＜0.

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目的：运用实时一个心动全容积三维超声心动图（以下简称4D）评价肺动脉高压（ pulnonary hypertension，PH）患者右心室收缩功能。方法：选取肺动脉高压（PH）患者38例及正常成人对照组25例，运用一个心动实时全容积三维超声心动图获取图像，经RVA 分析软件获取右室收缩末期容积（RVESV）、舒张末期容积（RVEDV）、每搏量（RVSV）和射血分数（ RVEF）等参数。结果：肺动脉高压组RVEDV、RVESV 较对照组比增大，差异有统计学意义（ P <0.05）；RVSV、RVEF 较对照组比较减小，差异有统计学意义（P <0.05）。结论：通过4D 成像技术可快捷、准确测定肺动脉高压患者右心室容积及收缩功能变化情况。肺动脉高压患者右室容积升高，右室收缩功能减退。
Objective Using one beat real-tine full-volune three-dinensional Echocardiography to evaluate Right Ventricular Sys-tolic Function in Patients with Pulnonary Hypertension. Method 38 patients with PH and 25 heathy cases included as controls were stud-ied. The end-diastolic volune(EDV),end-systolic volune(ESV),stroke volune(SV)and right ventricle ejection fraction(RVEF)of right ventricular were detected by one beat real-tine full-volune three-dinensional Echocardiography. Results Conpared to nornal control group,the value of EDV and ESV were significantly larger(all P<0. 05). RVSV and RVEF were reduced significantly(P<0. 05). Conclusion 4D can conveniently and accurately neasure RV volune and RVEF of pulnonary hypertension patients. Right ventricular vol-une increases and ejection fraction decreased in PH patient.

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目的探讨时间-空间相关成像技术(STIC)评估胎儿心脏收缩功能的价值。方法运用STIC技术采集160例健康孕妇胎儿的心动周期图像,后处理使用VOCAL法测量心室收缩末期和舒张末期容积,计算每搏心输出量(SV)、射血分数(EF)和每分心输出量(CO)。结果胎儿心室收缩末容积(VESV)、心室舒张末容积(VEDV)、SV和CO随孕周的增长而增加、射血分数(EF)不随孕周的变化而变化。胎儿右心室VESV、VEDV、SV、CO和EF均大于左心室。结论胎儿心脏收缩功能随孕周的增长而增加,右心收缩功能优于左心。
Objective To investigate the evaluation value of spatiotemporal image correlation (STIC) on fetal cardiac systolic function .Methods The fetal cardiac cycle images were collected by the four-dimensional(4D) STIC ultrasound technique in 160 normal singleton pregnancies .The virtual organ computer-aided analysis(VOCAL) technique was used to measure the ventricular end-systolic volume (VESV) and ventricular end -diastolic volumes(VEDV) .The stroke volume(SV) ,ejection fraction(EF) and cardiac output(CO) were calculated .Results VESV ,VEDV together with SV and CO in normal pregnancy were increased with gestation week increase .EF remained constant with advancing gestational week .VESV ,VEDV ,SV ,CO and EF of right ventricle were all larger than those of the left ventricle .Conclusion The fetal cardiac systolic function in normal pregnancy is increased with gestational age increase ,the right heart systolic function is superior to the left heart .

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目的观察实时三维超声心动图检测小儿法洛四联症(TOF)术前右心室收缩功能情况,并评估其临床应用价值。方法选取2013年1~12月收治的TOF患儿20例作为观察组研究对象,在术前实施RT-3DE与二维超声检测,对比观察两种超声检测的临床效果;另选择同期的20例正常健康体检儿童作为对照组,对比观察TOF患儿术前右心室收缩功能改变情况。结果观察组患儿术前右心室收缩/舒张末期容积、射血分数及每搏量等临床指标水平与对照组有明显差异,而对观察组患儿的两种超声检测结果亦有明显差异,差异均有统计学意义(P0.05)。结论 TOF患儿术前右心室收缩功能会出现明显变化,而RT-3DE检测能够通过右心室容积、射血分数等指标对其收缩功能进行有效评估,相比二维超声具有更为理想的临床检测效果与应用价值。
Objective To observe real-time three-dimensional echocardiography(RT-3DE) in testing systolic function of right ventricle before the surgery of tetralogy of Fallot(TOF) for children patients,and to evaluate its clinical value. Methods 20 children patients with TOF who were admitted to our hospital from January 2013 to December 2013 were selected as research subjects in an observation group.They received RT-3DE and two-dimensional ultrasonography before the surgery.Clinical effects of the two kinds of ultrasonography were observed and compared;20 healthy children during the same period were selected as a control group.Changes of systolic function of right ventricle for children patients with TOF were observed and compared. Results Clinical indices such as end-systolic/diastolic volume of right ventricle,ejection fraction and stroke volume for children patients before the surgery in the observation group were significantly different from those in the control group,and results of the two

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目的：探讨低钠血症与肺动脉高压( pulmonary arterial hypertension, PAH)预后的关系。方法对2009年1月-2011年11月武汉亚洲心脏病医院随访的PAH 50例的临床资料进行回顾性分析。结果低血钠组心率、右心房压、右心房面积指数、右心室面积指数、三尖瓣返流程度、右心房直径/左心房直径、右心室容积/左心室容积高于正常血钠组,心输出量指数、右心室每搏量指数、心输出量与肺动脉收缩压比值、三尖瓣环收缩期位移距离和左心室直径低于正常血钠组(P<0．05,P<0．01)。正常血钠组和低钠血症组1年和2年的存活率分别是93.33%、83.33%和50.00%、20.00%,低血钠组病死率高于正常血钠组(P<0．01)。结论血钠水平与PAH患者的病情严重程度及预后明显相关,低钠血症是PAH患者预后不良的重要指标。
Objective To explore the correlation between hyponatremia and the prognosis of patients with pul-monary arterial hypertension ( PAH) . Methods Clinical data of 50 PAH patients during January 2009 and November 2011 in Wuhan Asian Heart Hospital was retrospectively analyzed. Results Compared with those in normal serum sodi-um group, the values of heart rate ( HR) , right atrial pressure ( RAP) , right atrial area index ( RAAI) , right ventricular area index ( RVAI) , tricuspid regurgitation ( TR) , ratio of right atrial diameter to left atrium diameter ( RAD/LAD) and ratio of right ventricular end-diastolic volume to left ventricular end-diastolic volume ( RVEDV/LVEDV) were significant-ly higher in hyponatremia group, while the values of stroke volume index (SVI), right ventricular stroke work index ( RVSWI) , ratio of stroke volume to pulmonary arterial systolic pressure ( SV/PP) , tricuspid annular plane systolic ex-cursion (TAPSE) and left ventricle diameter (LVD) were significantly l

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目的 探讨实时三维心脏超声(RT-3DE)与电影磁共振(c-MRI)比较,在评估法洛四联症(TOF)术后右心功能中的应用价值.方法 2000年1月至2007年6月在复旦大学附属儿科医院心血管中心接受一期根治手术的37例TOF患儿同时接受了RT-3DE和c-MRI检查,分别测定右心室舒张末期容积(RVEDV)、右心室收缩末期容积(RVESV)、右心室射血分数(RVEF),分析2种技术在右心功能评价中的一致性及相关程度.结果 与c-MRI比较,RT-3DE在测量RVEDV、RVESV、RVEF上均有很好的相关性(r=0.933、0.943、0.911,P=0.000、0.000、0.105),能比较准确地反映RVEF,差异值仅为(1.2±4.5)％,但在RVEDV和RVESV上均被低估,分别低估约(-17.4±16.9)mL和(-9.3±10.5)mL.结论 RT-3DE与c-MRI比较,评估TOF术后右心容积和功能具有较高的相关性,能够准确反映RVEF,但在RVEDV、RVESV上存在低估,需要进一步研究来确定其在TOF术后右心功能评价上的可行性.
Objective To evaluate the clinical value of real-time 3 dimensional echocardiography (RT-3DE) for measurement of right ventricular function in the repaired tetralogy of Fallot (TOF) compared to cine magnetic resonance imaging (c-MRI).Methods Thirty-seven randomly selected patients with repaired TOF from Jan.2000 to Jun.2007 in Children''s Hospital,Fudan University underwent both RT-3DE and c-MRI for the data of right ventricular enddiastolic volume (RVEDV),right ventricular end-systolic volume (RVESV),right ventricular ejection fraction (RVEF),which were compared to evaluate the reproducibility and correlation of two ways on right ventricular function.Results All the patients completed both RT-3DE and c-MRI on the same day.The correlation for RVEDV,RVESV,RVEF measured by 2 methods was high (r =0.933,0.943,0.911,P =0.000,0.000,0.105),and it showed that consistency existed in RVEF,as difference was only (1.2 ± 4.5) ％.Comparison with c-MRI,RVEDV and RVESV measured by RT-3DE wa

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目的 观察慢性肺源性心脏病(简称肺心病)患者心脏MRI(CMRI)心肌增强成像特征.方法 前瞻性纳入确诊为慢性肺心病患者21例,包括18例慢性血栓栓塞性肺动脉高压及3例特发性肺动脉高压患者.所有患者均行CMRI,采用回顾性心电门控真实稳态自由进动梯度回波序列获得从心尖至心底8～10层心室短轴两腔心电影图像,采用前瞻性时间调整敏感度编码梯度回波序列获得心肌首过灌注图像,采用相位敏感反转恢复(PSIR)T1WI序列获得心肌延迟增强显像.采用Argus软件测定延迟期强化心肌体积与右心室功能参数,采用Spearman相关分析评价延迟期强化心肌体积与右心室功能参数的相关关系.结果 21例肺心病患者CMRI均显示不同程度右心房及右心室扩大,室间隔向左心室膨隆,左心房及左心室受压缩小.CMRI测定脊柱室间隔夹角为(70±11).,右心室舒张末期容积为(205±48)ml,收缩末期容积为(141±33)ml,每搏输出量为(64±21)ml,射血分数为(32±11)％,心肌质量为(100±37)g.心肌首过灌注增强成像显示心肌均匀增强,未见局限性异常灌注区.21例患者延迟强化,均在右心室游离壁与室间隔移行带(IP)部心肌中层出现三角形延迟强化灶,1例除IP部出现延迟强化外,室间隔中层心肌出现线状延迟强化,心肌延迟强化病灶体积为(13
Objective To determine the characteristics of contrast enhanced-cardiovascular magnetic resonance imaging (CE-CMRI) in patients with cor pulmonale.Methods Twenty-one patients with cor pulmonale were prospectively included and underwent CMRI.Short-axis cine images of the heart were obtained for ventricular function assessment using a steady-state free precession sequence.For first-pass perfusion,a Turbo FLASH was performed after intravenous administration of 0.2 mmol/kg Gadopentetate dimeglumine.For delayed contrast enhancement (DCE),a short-axis phase-sensitive inversion recovery sequence was performed.Right ventricular function and myocardial contrasted volume in DCE were measured with Argus software.Spearman correlation analysis was conducted to examine the association between myocardial contrasted volume and right ventricular function.Results CMRI showed the enlarged right atrium and ventricle,bowing ventricular septum in 21 patients.Septal angle was (70± 11)°,Right vent

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目的评估时间-空间关联成像(spatio-temporal image correlation,STIC)技术在孕21~32+6周正常胎儿及心律失常胎儿心功能检查中的应用价值。方法使用GE voluson E8彩色多普勒超声诊断仪STIC技术对孕21~32+6周的60例正常胎儿及12例单纯性心律失常胎儿扫描,获得胎儿心脏整个心动周期的容积数据,存盘后采用虚拟器官计算机辅助分析软件(virtual organ computer aided analysis,VOCAL)进行脱机分析,手动勾勒出心室舒张末期容积(end-diastole volume,EDV)及收缩末期容积(endsystole volume,ESV)。计算心室的每搏量(stroke volume,SV)、心排血量(cardiac output,CO)和射血分数(ejection fraction,EF),统计分析左/右心室EDV、ESV、SV、CO和EF的正常参考值及其与孕龄的相关性,随访所有胎儿结局。结果 60例正常胎儿心功能,21~32+6周正常胎儿不同孕龄左心室及右心室的EDV、ESV、SV及CO的正常参考值均随孕龄的增长而增加,与孕龄呈正相关(P均0.001);孕21~32+6周正常胎儿左心室射血分数(left ventricular ejection fraction,LVEF)和右心室射血分数(right ventricular ejection fraction,RVEF)的正常参考值分别为55%~57%、53%~56%,2者与孕龄有负相关性(r=-0.41、-0.41,P均为0.001)。12例单纯性心律失常胎儿心律失常类型包括房性期前收缩7例、心动过缓2例(短暂心动过缓后均可恢复正常心律)、房早伴短阵房速1例、房早伴房室传导阻滞1例及不能明确类型1例。12例心律失常胎儿LVEF(波动范围48%~66%)和RVEF(波动范围48%~64%)大致正常;左/右心室EDV、ESV、SV及CO与相应孕周正常胎儿参考值相比大致正常。12例胎儿均足月分娩,随访至新生儿均身体健康。结论 STIC技术能较为准确、客观的测量胎儿心室容积及评价胎儿心功能,对心律失常胎儿的心功能评估也有一定价值。
Objective To assess the application of spatio-temporal image correlation( STIC) for normal and arrhythmic fetal cardiac function examination from 21 to 32+6 gestational weeks. Methods Fetal heart ventricular end-diastole volumes( EDV) and end-systole volumes(ESV) were measured with STIC and virtual organ computer aided analysis(VOCAL) in 60 normal fetuses and 12 fetuses with isolated arrhythmia from 21 to 32+6 gestational weeks. The stroke volume(SV), cardiac output(CO) and ejection fraction(EF) of each ventricle were calculated with EDV and ESV. The normal reference values of EDV, ESV, SV, CO and EF of left and right ventricles were calculated with statistical methods. The correlation between cardiac parameters( including EDV, ESV, SV, CO and EF) and gestational age were analyzed. Every fetus had a follow-up outcome after birth. Results The cardiac functions of 60 normal fetuses:We obtained the normal reference values of EDV, ESV, SV and CO of left and right ventricles according to di

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