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双语推荐：术前分期

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目的 评价三维断层超声成像(TUI)技术在宫颈癌术前分期中的应用价值.方法 对87例经组织活检确诊为富颈癌患者进行经阴道TUI检查,并参考FIGO(2009)分期标准对患者进行超声术前分期,以手术病理结果或盆腔磁共振(MR)检查结果为金标准,比较超声术前分期和临床术前分期的准确性.结果 使用TUI技术对宫颈癌术前分期的准确率较临床分期准确率高,差异有统计学意义(91.95％对81.60％,P＜0.05).其中,ⅡB期超声术前分期准确率为90％,临床术前分期准确率为30％,差异有统计学意义(P＜0.05).结论 与临床术前分期相比,TUI技术有助于提高宫颈癌术前分期准确率,是一项较有临床价值的检查方法.
Objective To evaluate the clinical value of tomography ultrasonic imaging (TUI) in staging carcinomas of the cervix.Methods Eighty-seven patients with biopsy proven cervical cancer who underwent transvaginal TUI examination were enrolled.Clinical and ultrasonic staging were based on the FIGO staging system.Surgical-pathological or MR results was taken as golden standard.Ultrasonic staging were compared with clinical staging.Tumor sizes of 38 cases of cervical cancers measured by TUI were recorded and compared with the pathological results.Results The overall accuracy of preoperative TUI staging was higher than that of preoperative clinical staging (91.95 ％ vs 81.60 ％,P ＜0.01).Mean size of the 38 malignant tumors was 2.5 cm×2.1 cm×2.2 cm by TUI and 2.6 cm×2.1 cm×2.3 cm by pathological samples (P ＞ 0.05).Conclusions TUI technology may be useful in the noninvasive examination of preoperative staging of carcinoma cervix.

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目的探讨磁共振成像(magnetic resonance imaging,MRI)在Ⅰ、Ⅱ期子宫内膜癌术前分期中的价值。方法对52例经分段诊刮及病理检查证实的子宫内膜癌患者行MRI检查,并进行术前分期,将术前分期与手术病理分期结果进行比较。结果 52例子宫内膜癌按照FIGO 2009分期标准,MRI判断为ⅠA期31例,ⅠB期15例,Ⅱ期6例,MRI对子宫内膜癌分期与病理分期显著相关(P0.05)。术前MRI分期ⅠA期、ⅠB期、Ⅱ期敏感性分别为90.3%、86.7%、83.3%,特异性分别为90.5%、89.2%、100%,准确率分别为90.4%,82.1%、98.1%。结论 MRI对Ⅰ、Ⅱ期子宫内膜癌术前分期准确性高,可以作为常规检查手段。
Objective To discuss the value of magnetic resonance imaging ( MRI ) in preoperative staging of stageIandIIendometrialcarcinoma.Methods 52patientswithendometrialcarcinomaconfirmedbycurettageand pathological examination were taken MR examination , and preoperative staging was performed , preoperative staging and surgical pathological staging results were compared .Results According to the FIGO 2009 criteria, in the 52 cases with endometrial carcinoma ,31 cases were diagnosed as stage ⅠA,15 cases as stage ⅠB and 6 cases as stageⅡ by MRI, MRI in preoperative staging of endometrial carcinoma and pathological staging had significantly relationship(P<0.05).The sensitivity of MRI preoperative stage of ⅠA,ⅠB,Ⅱwere 90.3%, 86.7%, 83.3%, specificity were 90.5%, 89.2%, 100% and accuracy were 90.4%, 82.1%, 98.1%.Conclusion MRI is an accurate method in preoperative staging for stage I and II endometrial carcinoma , which can be used as a routine examination.

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探讨64层MSCT对进展期胃癌术前T分期的准确性。方法:搜集经术前胃镜及病理活检证实的100例胃癌患者的病例资料,对其进行常规平扫及三期动态增强扫描后进行术前T分期,并与术后病理T分期对照,分期的准确性采用Kappa一致性检验。结果:MSCT对T2、T3、T4期胃癌分期的敏感度为58.33%、88.24%、80.95%;特异度为97.22%、75.76%、93.65%;符合率为91.67%、82.14%、90.48%,T分期总的符合率为82.14%。结论:64层MSCT在进展期胃癌术前T分期中具有较高的准确性,对于胃癌术前评估及预后具有重要的指导意义。
Objective:To study the accuracy of 64-slice spiral CT (MSCT)in the diagnosis of T-staging of advanced gastric cancer before surgery.Methods:Clinical materials of 100 patients with gastroscopy and biopsy proved gastric cancer were recruited.MSCT were performed with plain and triphasic dynamic contrast enhancement before surgery.T-staging was evaluated and correlated with that of pathology.Kappa consistency test was used to study the accuracy.Results:The sensi-tivity of MSCT for T-staging of T2、T3 and T4 was 58.33%、88.24% and 80.95%,respectively.The specificity for T2、T3 and T4 was 97.22%、75.76% and 93.65% ,respectively.The accuracy for T2、T3 and T4 was 91.67%、82.14% and 90.48%,respectively.The accuracy on T-staging as a whole was 82.14%.Conclusion:Relatively high accuracy in T staging of advanced gastric cancer before surgery could be obtained by 64-slice MSCT,and it can provide reliable information for surgery guidance and prognosis prediction.

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目的：探讨超声微探头在食管癌T、N分期的准确率及食管癌术前诊断的价值。方法选择手术治疗的89例食管癌患者术前接受超声微探头检查，以手术探查和术后病理诊断结果为标准，评价超声微探头诊断食管癌浸润深度（T分期）和局部淋巴结转移（N分期）的准确率。结果超声微探头检查诊断食管癌T110例，T2分期16例，T3分期45例，T4分期18例，与术后病理结果对照，肿瘤的T分期的准确率为89%（80/89），N分期的准确率为76%（68/89）。结论超声微探头检查是诊断食管癌术前分期的有效方法，对指导术前制定治疗方案，评价预后有重要意义。
Objective To study the relationship between the Klotho gene polymorphism in exon 2, rs9536314 and rs9527025 and 4 Zone District rs564481, polymorphism of rs1207568 in the promoter region and longevity in Hetian Uygur population. Methods Genotyping were done regarding polymorphism of rs9536314 and rs9527025 and rs1207568 and the rs564481 in 112 cases of case group and 249 cases of control group by Multiplex SNaPshot reaction. Results There are no significant difference between case group and control group regarding genotype frequency, al ele frequency and haplotype distribution in rs9536314, rs9527025, rs1207568 and rs564481 of Klotho gene (P>0.05). Polymorphism of Klotho gene is not related to longevity the Uygur population according to correlation analysis (P>0.05).Conclusions There are no correlation between polymorphism of Klotho gene in rs9536314, rs9527025 , rs1207568 and rs564481 and longevity in Xinjiang Uygur population.

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目的：探讨CT能谱成像最佳 keV单能量图像及能谱曲线在胃癌术前 T分期中的应用价值。方法前瞻性地收集经胃镜活检确诊为胃癌的患者52例,术前采用CT增强能谱扫描,2名观察者分别独立分析混合能量图像及单能量图像并进行 T 分期,以术后病理分期作为金标准,比较二者在胃癌术前 T 分期中的准确率及观察者间一致性。结果 CT 能谱成像对胃癌术前 T分期的准确率(82.69%,43/52)较混合能量图像(71.15%,37/52)显著提高(P=0.031)。CT能谱成像胃癌术前T分期观察者间一致性(Kappa=0.768)优于混合能量图像(Kappa=0.562)。结论 CT能谱成像最佳 keV单能量图像及能谱曲线有助于提高胃癌术前T分期的准确率。
Objective To evaluate the application of CT spectral imaging,best keV monochromatic images and spectral curves,in preoperative T staging of gastric cancer.Methods Fifty-two patients with gastroscopically confirmed gastric cancer were included prospectively and underwent preoperative contrast enhanced CT spectral imaging.Two radiologists read poly-and monochromatic CT images of 52 patients and assessed T staging independently.With the reference of postoperative histopathological findings,T staging accuracy and interobserver agreement were compared between poly-and monochromatic CT images.Results Preoperative T staging accuracy of gastric cancer by spectral imaging (82.69%,43/52)was significantly higher than that of polychromatic CT images (71.15%,37/52)(P=0.031).Interobserver agreement (Kappavalue)was improved from 0.562(polychromatic CT images)to 0.768 (spectral imaging).Conclusion CT spectral imaging,best keV monochromatic images and spectral curves,can improve preoperative T stag-ing

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目的：探讨经直肠超声联合增强CT扫描对直肠癌术前分期的临床价值。方法选取69例直肠癌患者，分别行经直肠超声及增强CT扫描，并同术后直肠癌病理T、N分期结果作对照，分析经直肠超声联合增强CT扫描对直肠癌术前T分期及N分期的诊断准确率。结果经直肠超声诊断直肠癌术前T分期准确率高于增强CT扫描，经直肠超声联合增强CT扫描诊断直肠癌T分期准确率高于单独经直肠超声及增强CT扫描，差异具有显著性（P＜0.05）。经直肠超声诊断直肠癌术前N分期准确率高于增强CT扫描，经直肠超声联合增强CT扫描诊断准确率高于单独经直肠超声及增强CT扫描，差异具有显著性（P＜0.05）。结论经直肠超声联合增强CT扫描可提高直肠癌术前分期的诊断准确率，为临床评估病情、选择治疗方案提供重要依据。
Objective To investigate the transrectal ultrasound combined with contrast enhanced CT scan in preoperative staging of rectal cancer and the clinical value. Method 69 cases of patients with ractal were selected and underwent transrectal ultrasound and enhanced CT scan, and compared the T, N results with the postoperative pathological staging of rectal cancer. Analysed of transrectal ultrasound combined with contrast enhanced CT scan in preoperative diagnosis of rectal cancer T staging and N staging accuracy. Result Transrectal ultrasound in diagnosis of colorectal cancer T staging accuracy was higher than that of contrast enhanced CT scan, transrectal ultrasound combined with enhanced CT scan in the diagnosis of rectal cancer T staging accuracy was higher than that of single application of transrectal ultrasound and enhanced CT scan, the difference was signiifcant (P<0.05). Transrectal ultrasound in the diagnosis of preoperative N staging accuracy was higher than that of cont

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目的探讨多层螺旋CT仿真膀胱镜(multi-slice spiral CT virtual cystoscopy,MSCTVC)对膀胱癌术前诊断及临床分期的价值。方法 22例经手术病理证实为膀胱癌的患者,术前分别行MSCT双期增强扫描,同时结合仿真内镜图像进行分析及普通纤维膀胱镜检查,比较两种方法的膀胱癌检出率,分析MSCTVC对膀胱癌术前分期的准确性。结果 22例患者共发现病灶25个,MSCT及MSCTVC总体检出率为100%(25/25),高于膀胱镜检查(92%,23/25)。单纯双期增强MSCT分期:T113例、T2a5例、T2b5例、T31例、T41例;结合仿真膀胱镜成像后分期:T113例、T2a4例、T2b5例、T32例、T41例;术后病理分期:pTl13例、pT2a5例、pT2b4例、pT32例、pT41例。MSCT多期增强扫描对膀胱癌术前分期总体准确率为72%(18/25),结合仿真膀胱镜成像对膀胱癌分期总体准确率为88%(22/25)。与术后病理分期相比,MSCTVC对膀胱癌术前分期的一致性(k=0.818)高于MSCT扫描术前分期一致性(k=0.574)。尤其当肿瘤浸润膀胱壁外结构时(≥T3期)时,MSCTVC的术前分期准确率为100%,与术后病理分期完全一致(k=1)。结论 MSCTVC是一种安全、无创、有效的检查方法,在膀胱癌术前诊断及临床分期中具有重要价值。
Objective To discuss the value of double-phase enhancement multi-slice spiral CT and virtual cystoscopy (MSCTVC)using oxygen as contrast in the diagnosis and clinical staging of preoperative bladder cancer. Methods Twenty two patients with bladder cancer diagnosed by oper-ation.All of them were examined both by double-phase enhancement and virtual cystoscopy using oxygen as contrast and conventional cystoscopy.The sensitivity of the diagnosis and the accuracy of the clinical staging of preoperative bladder cancer were compared. Results There were 25 lesions to be found.The sensitivity of MSCT and MSCTVC was 100% (25/25),that is higher than the sen-sitivity of the conventional cystoscopy.The staging of MSCT:Tl 13 cases,T2a 5 cases,T2b 5 cases, T3 1 case,T4 1 case.The staging of MSCTVC using oxygen:Tl 13 cases,T2a 4 cases,T2b 5 cases, T3 2 cases,T4 1 case.Histopathological results:pTl 13 cases,pT2a 5 cases,pT2b 4 cases,pT3 4 ca-ses,pT4 1 case.The sensitivity of preoperative staging on bl

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目的探讨多层螺旋CT(MSCT)在胃癌术前临床分期中的价值。方法对该院2011年4月至2012年8月收治的43例经胃镜及术后证实的胃癌患者术前进行MSCT扫描,所得图像在后处理工作站进行后处理,观察胃癌病变情况、胃周淋巴结大小及远处转移,按国际统一的TNM分期法进行术前分期,其结果与术后病理TNM分期对照。结果 MSCT对胃癌T分期的总准确率为83.7%(36/43);对N分期的总准确率为72.1%(31/43);对M分期的总准确率为93.0%(40/43)。结论利用MSCT的各种图像后处理技术能提高胃癌术前TNM分期的准确率,对外科制订合理的治疗方案有较高价值。
Objective To explore the value of multi-slice spiral CT(MSCT) in the preoperative staging of gastric carci-noma. Methods MSCT was performed in 43 patients with gastric carcinoma diagnosed by biopsy before operation in this hospital from April 2011 to August 2012 ,and the obtained images were postprocessed by post-processing station to observe gastric neo-plastic lesion,sizes of lymph nodes and distant metastasis,and phased preoperatively according to the world-wide TNM staging method,the results of which were compared with post-operatively pathological TNM staging method. Results The accuracy of MSCT was 83.7%(36/43) in T stage,72.1%(31/43) in N stage and 93.0%(40/43) in M stage. Conclusion Various images post-processing technology of MSCT can improve the accuracy of pre-operative TNM staging of gastric carcinoma,and it has higher value in formulating surgical therapeutic schedule..

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目的：探讨3.0T MRI 与64层螺旋 CT 在进展期胃癌术前 T 分期中的诊断价值。方法对经胃镜病理证实的胃癌患者40例,于术前1周行 MSCT 及 MRI 检查,根据影像学资料进行 T 分期,并与术后病理结果进行对照。结果MRI 与 MSCT 术前 T分期与术后分期均有较好的一致性(Kappa-test ,P 0.05)。结论MRI 与 MSCT 在进展期胃癌术前 T 分期中诊断价值相当,MRI的诊断准确性稍高于 MSCT,尤其是在区分 T3、T4期具有潜在的优势。
Objective To explore the differential diagnosis value in preoperative T-staging of advanced gastric cancer with 3.0T MRI and 64-slice spiral CT.Methods 40 patients with advanced gastric cancer confirmed by gastroscopy and biopsy were admin-strated MRI and MSCT examination one week before surgery.Then the T-staging were evaluated by MRI and pathology.Results There was a good consistency of T-staging between MRI and MSCT compared with biopsy (Kappa-test ,P 0.05).Conclusion MRI is comparable to MSCT in the T-staging of the advanced gastric cancer,and the accuracy of MRI is seperior to MSCT,especially in T3 and T4 stage.

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目的 探讨CT诊断在食管癌术前淋巴结转移临床分期中的意义.方法 对103例已手术食管癌患者临床资料进行回顾性分析,所有患者术前均接受双源CT检查,根据淋巴结是否肿大得出术前的淋巴结分期,再与术后的病理分期进行对照分析.结果 术前CT中淋巴结肿大患者29例（28.2％）,术后病理证实有淋巴结转移患者70例（68.0％）.CT诊断与术后病理两种淋巴结分期诊断的阳性率结果不一致（x2=11.719,P=0.001）.CT诊断为淋巴结转移阳性患者比阴性患者术后病理分期晚（Z=-3.04,P=0.002）,但两种诊断方法之间不存在相关性（x2=10.885,r=0.055,P=0.055）.结论 术前通过CT判断淋巴结转移的临床分期准确率不高,建议联合PET-CT、超声内窥镜等检查得到更准确的临床分期.
Objective To assess the rationality of using CT for clinical staging in esophageal carcinoma.Methods 103 esophageal carcinoma patients with radical resection were selected,patients were examined by CT before surgery.To compare the clinical staging on the basis of CT findings with pathology.Results Lymph node enlargement were mentioned in 29 cases (28.2 ％) with CT findings before surgery,but 70 cases (68.0 ％) by pathology.The CT findings and pathology were inconsistent (x2 =11.719,P =0.001).Although the pathology staging in the cases which were positive with CT findings could be later (Z =-3.04,P =0.002),there was no correlation between the two methods (x2 =10.885,r =0.055,P =0.055).Conclusion The accuracy rate in esophageal carcinoma clinical staging by CT before surgery is low.Combining with PET-CT or endoscopic ultrasonography may improve the accuracy rate.

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