目的观察桑杷止咳汤治疗慢性支气管炎急性发作的临床效果。方法选择2012年8月至2013年8月在新疆昌吉回族自治州中医医院门诊就诊的慢性支气管炎急性发作患者180例,按随机数字表法将患者分为桑杷止咳汤治疗组和西医治疗对照组,每组90例。两组均给予一般治疗,桑杷止咳汤治疗组在一般治疗的基础上加服桑杷止咳汤(组成:桑白皮10g,枇杷叶10g,鱼腥草10g,蜜紫菀15g,蜜款冬花6g,浙贝母12g,苏子10g,白芥子6g,桔梗10g,白前12g,陈皮6g,百部6g)每日1剂,水煎分2次服用;西医治疗对照组给予控制感染、止咳化痰等治疗方法,疗程均为7d。观察两组治疗前后中医证候疗效和咳嗽症状量化评分的变化。结果桑杷止咳汤治疗组治愈率明显高于西医治疗对照组[70.00%(63/90)比33.33%(30/90),P〈0.01]。两组治疗前咳嗽症状量化评分比较差异无统计学意义,治疗后咳嗽症状量化积分均较治疗前明显降低,且以桑杷止咳汤治疗组降低更显著(分:1.66±1.12比4.36±2.32,P〈0.01)。结论桑杷止咳汤治疗慢性支气管炎急性发作疗效显著。
Objective To observe the clinical effect of Sangpa Zhike decoction in the treatment of acute exacerbations of chronic bronchitis. Methods 180 patients with acute exacerbation of chronic bronchitis admitted to Autonomous Prefecture Hospital of traditional Chinese medicine(TCM)in Changji,Xinjiang,from August 2012 to August 2013 were enrolled. They were divided into Sangpa Zhike decoction treatment group and western medicine treatment control group by random number table,90 cases in each group. General treatments were given to the two groups. In the Sangpa Zhike decoction treatment group,additionally only oral Sangpa Zhike decoction was given(composition:Morus alba 10 g,loquat leaf 10 g,Houttuynia 10 g,honey aster 15 g,honey coltsfoot flower 6 g,Zhejiang Fritillaria 12 g,perilla 10 g,white mustard seed 6 g,Platycodon grandiflorum 10 g,Rhizoma Cynanchi Stauntonii 12 g,tangerine peel 6 g,Stemona 6 g). The ingredients were mixed in water and boiled to form a decoction,one dose daily,divided