Rob Nixon''s 2005 article, named Environmentalism and Post-colonialism, has historicly combined eco-criticism and post-colonialism. Later, his masterpiece, Slow Violence and the Environmentalism of the Poor (2011), is sensational in both postcolonial studies and ecocritical studies, becoming an immediate classic for both fields. This article attempts to introduce the twofields'' reconciliation and collision in Western academia from an epistemological perspective, and to illustrate the epistemological motives, historical backgrounds, and prospective research for postcolonial eco-criticism led by Rob Nixon. It hopes to provide some fresh ideas for emerging Chi-nese researches on postcolonial eco-criticism.