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双语推荐:表皮系数

目的探讨磁共振扩散加权像(DWI)及表观扩散系数对卵巢表皮样囊肿的诊断价值。方法回顾性分析11例经手术病理证实的卵巢表皮样囊肿患者磁共振常规及扩散加权成像,选取感兴趣区,测量表观扩散系数进行分析。结果磁共振平扫11例T1WI呈低信号,T2WI为高信号,DWI呈高信号,表观扩散系数(ADC)值降低,ADC值范围为(0.632~1.082)×10-3 mm2/s。结论通过对卵巢表皮样囊肿磁共振表现的分析,提示扩散加权成像对卵巢表皮样囊肿诊断有一定特异性。
Objective To study the value of diffusion-weighted MR imaging(DWI) and apparent diffusion coeffi-cient(ADC) in the diagnosis of ovarian epidermoid cyst. Methods The MRI and DWI data of 11 cases with ovarian epidermoid cyst confirmed by surgery and pathology were analyzed retrospectively. Results All 11 cases were demonstrated as hypointensity on T1 weighted imaging (T1WI) and hyperintensity on T2 weighted imaging (T2WI) and DWI, and the ADC value was reduced, with the range of (0.632~1.082)×10-3 mm2/s. Conclusion Ovarian epidermoid cyst analyzed by the MRI and DWI has some characteristics which contributes to the clinical diagnosis of ovarian epidermoid cyst.

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目的 研究特应性皮炎(AD)患者皮肤屏障功能情况,并分析其与水闸蛋白1(claudin-1)表达的相关性.方法 纳入AD患者和健康人各1 1例.应用皮肤经表皮失水率测定仪和皮肤高频超声检测仪测定受试者经表皮失水率、表皮厚度与表皮致密度,并用双抗体夹心ELISA法定量检测血清中脱落claudin-1表达量.应用单因素方差分析和t检验比较不同组别之间相关参数的差异;应用Pearson相关系数分析不同参数之间的相关性.结果 AD患者皮疹部位经表皮失水率为(36.9±34.2) g·m-2·h-1,非皮疹部位为(9.1±6.0) g·m-2·h-1,均高于健康对照[(4.4±3.1)g·m-2·h-1];AD患者皮疹部位表皮厚度(0.23±0.04) mm,显著高于非皮疹部位[(0.18 ± 0.03) mm]和健康对照[(0.18±0.02) mm].AD患者皮疹部位有其特征性表皮下低回声带.AD患者claudin-1表达量为(0.80±0.88) ng/ml,显著低于健康人[(1.73±1.85) ng/ml];claudin-1与表皮厚度显著负相关(r=-0.61),与经表皮失水率的倒数显著正相关(r=0.44).结论 AD患者损伤的皮肤屏障功能与claudin-1表达相关,屏障功能状态可用经表皮失水率、经表皮失水率倒数和表皮厚度进行定量表述.
Objective To evaluate skin barrier function in patients with atopic dermatitis (AD),and to assess its relationship with claudin-1 expression.Methods Totally,11 patients with AD and 11 healthy human controls were recruited in this study.A Tewameter TM210 was used to measure transepidermal water loss (TEWL) value,and high-frequency ultrasound to determine epidermal thickness and density,in lesional and non-lesional skin of the patients and normal skin of the healthy controls.A double-antibody sandwich enzyme-linked immunosorbent assay (ELISA) was performed to determine the serum level of free claudin-1 in these subjects.One-way analysis of variance and t test were carried out to compare these parameters in different groups,and Pearson''s correlation analysis to estimate the relationship between different parameters.Results The TEWL value was significantly higher in lesional skin than in nonlesional skin of patients with AD and normal skin of the healthy controls ((36.9 ± 34.2)

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土库曼斯坦阿姆河右岸是一个高含硫化氢和二氧化碳的复杂底水块状碳酸盐岩气田。气田储层类型多样,非均质性严重,根据储层特征,实施了以常规酸与转向酸酸化相结合的增产措施。对现场24井次的酸化作业进行了系统的施工参数分析和技术评估。采用Paccaloni评估方法计算了酸化后表皮系数,根据曲线特征将施工曲线分为5类,分别为明显解堵型、明显漏失型、突破后漏失型、双层突破型和未明显突破型。通过表皮系数变化、曲线特征分析及措施效果对比对储层进行深入认识,进一步优化了对阿姆河右岸气田酸化措施的适用条件和施工参数,对提高气田二期开发的增产效果具有重要意义。
Amu Darya Right Bank gas ifeld, Turkmenistan is a complex faultblock gas ifeld with bottom water, high in hydrogen sulifde and carbon dioxide content. The reservoirs are diverse in types and strong in heterogeneity. According to reservoir characteristics, the stimulation combining conventional acidizing with diverting acidizing was developed and carried out. The operation parameters and technologies of 24 wells acidized were systematically assessed. Paccaloni evaluation method was used to calculate skin factor after acidizing, the treatment curves were divided into ifve categories according to the curve characteristics, namely, obvious plugging re-moval type, obvious loss type, loss after plugging removal type, double plugging removal type and non-obvious breakthrough type. The analysis of the skin factor variation, curve characteristics and comparison of stimulation effect gave better understanding on the reservoir. The applicable conditions and treatment parameters of acidizing in th

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在拟径向流阶段,有效井筒半径是无因次裂缝导流能力的一个函数。在此基础之上,提出了新的简单实用压后气井产能评价公式。通过文献中两个实例的计算对比验证了该公式的可靠性。分析了多种因素对气井产能影响的强弱程度,结果表明由强到弱的因素依次为地层压力、地层温度、有效厚度、渗透率、裂缝半长、表皮系数、裂缝导流能力。要提高气井产能,行之有效的手段是通过酸化压裂等增产措施来解除近井地带表皮污染和建立高导流能力的渗流通道。
In the pseudoradial flow period, an effective wellbore radius is like a function for dimensionless fracture diverting capaci-ty (FCD). On this basis, a new simple and practical deliverability evaluation formula of fractured gas well is proposed. The reliabili-ty of the formula was proved by comparing two examples calculation in literatures, thereby analyzing the degree of various factors in-fluencing gas well deliverability. The results show that the order of factors from strong to weak is formation pressure, formation tem-perature, effective thickness, permeability, fracture half-length, skin factor, fracture conductivity. In order to improve gas well pro-ductivity, the effective means are using stimulation treatment of fracturing and acidizing, which can resolve near-well formation damage and establish flow channel with high flow conductivity.

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以5个鹅掌楸种源的1年生苗木成熟叶片为材料,对叶表皮、叶片横切面及主脉横切面的16个解剖性状进行观察和变异性分析。结果表明:鹅掌楸叶解剖性状在种源间及种源内存在极丰富的变异,除下表皮密度在种源间差异不显著外,其余性状在种源间及种源内(包括下表皮密度)均存在极显著差异。种源间的平均表型分化系数为27.5%,说明鹅掌楸叶片结构的主要性状存在于种源内的变异(72.5%)远大于种源间的变异。鹅掌楸叶的解剖性状与地理生态因子的相关分析表明,其种源间的变异呈现梯度规律性,表皮各性状与经度、年均温呈负相关关系,叶片和主脉横切面各性状与经度、纬度大部分呈正相关关系,而与年降水量、年均温大都呈负相关关系。用种源间欧式距离进行UPGMA聚类,可将5个种源的鹅掌楸划分为3个类群。
Using the mature leaves of one-year old seedlings of five Liriodendron chinense provenances as materials, the 16 anatomical traits of leaf epidermis,leaf cross section and main vein cross section were observed and variance analyzed.The results showed that there were abundant variances in leaves anatomical traits among/within L . chinense provenances.Highly significant differences existed in all anatomical traits among/within provenances except the lower epidermis density among provenances.The mean phenotypic differentiation coefficient was 27.5%;this in-dicated the variation of main leaves anatomical traits within provenances (72.5%)was obviously higher than that of traits among provenances.The correlations among the anatomical features,geography and climate were also analyzed. The results indicated that the variations among provenances had the gradient regularity,and there were negative cor-relations between all epidermis traits and longitude and mean annual temperature.Most of traits

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首次将经验模态分解方法引入湍流稳定性分析,与传统的线性和滑动平均去势方法进行了比较,发现经验模态分解方法的去势效果最好。基于“南海平台通量观测计划”(FOPSCS)近两年的连续通量观测数据,得到了22476个摩擦速度的估算值,结果表明,当风速小于5 m/s 时,拖曳系数随风速增大而减小,而风速大于5 m/s 时,拖曳系数随风速增大而增大,两种情形分别反映了黏性表皮摩擦和波浪引起的形状阻力对海面风应力的贡献。同时发现短风区情形的拖曳系数大于长风区情形,说明波浪成长状态会对海-气界面动量交换产生影响。
The empirical mode decomposition (EMD)method is introduced to analyze the stability of turbulence for the first time and is compared with the traditional detrending methods,like linear detrending(LDT)and running mean filtering (RMF).The results show that EMD is the most reliable method to obtain momentum flux at the air-sea surface.Based on about two years of data from Flux Observation on Platform in South China Sea (FOP-SCS)project,22 476 friction velocities were obtained.It was found that when the wind speed is less than 5 m/s, the drag coefficient decreases with the increase of wind speed;whereas,the trend is opposite when wind speed is greater than 5 m/s.These two different cases reflect the contribution to the wind stress from the roughness gener-ated by viscous boundary-layer and wave-induced form drag,respectively.Further analysis shows that the drag co-efficient with limited fetch condition is larger than that with unlimited fetch,which revealed the wave age can also influence

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研究目的:比较花椒挥发油与其主要成分作为经皮促透剂的皮肤细胞毒性,对系列不同油水分配系数药物促透作用特征及其作用机制。 创新要点:选择系列不同油水分配系数中药活性成分简化并表征中药制剂中复杂有效成分,对比研究花椒挥发油与其主要成分的经皮促透作用特征差异。 研究方法:利用表皮角质形成细胞(HaCaT)和真皮成纤维细胞(CCC-ESF-1)测定其皮肤细胞毒性,选择系列不同油水分配系数中药活性成分作为模型药物测定花椒挥发油与其主要成分的经皮促透作用特征差异,并在此基础上采用傅利叶变换红外光谱(FTIR)等研究其促透作用机制。 重要结论:花椒挥发油相对于其单一组成成分具有更好的经皮促透效果。
Our previous studies had confirmed that the essential oil from Zanthoxylum bungeanum Maxim. (Z. bungeanum oil) could effectively enhance the percutaneous permeation of drug molecules as a natural transdermal penetration enhancer. The aim of the present study is to investigate and compare the skin penetration enhancement effect of Z. bungeanum oil and its main components on traditional Chinese medicine (TCM) active components. Toxicities of Z. bungeanum oil and three selected terpene compounds (terpinen-4-ol, 1,8-cineole, and limonene) in epidermal keratinocytes (HaCaT) and dermal fibroblast (CCC-ESF-1) celllines were measured using an MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay. Five model drugs in TCM external preparations, namely osthole (OT), tetramethylpyrazine (TMP), ferulic acid (FA), puerarin (PR), and geniposide (GP), which were selected based on their lipophilicity denoted by logKo/w, were tested using in vitro permeation studies in which
目的研究青藏高原25种灌木叶片解剖结构和气孔特征,了解其水分适应机制,为青藏高原地区造林筛选优良耐旱植物提供参考依据.方法通过常规石蜡切片技术,对比叶片角质层、上下表皮、栅栏组织、海绵组织和叶片厚度等12项指标,运用主成分分析和隶属函数法对供试植物进行抗旱性能分析与评价.结果和结论25种植物叶片具有典型的旱生结构,叶片厚度最高为323.00μm、平均为186.25μm,上表皮角质层厚度最高为4.83μm、平均为1.71μm,上表皮平均比下表皮厚30.00%,气孔小而密集,这是植物长期适应高原干旱环境的进化结果,12项指标的种间差异极显著.通过主成分分析法结合各指标的变异系数筛选出5项具有代表性的抗旱指标:气孔密度、叶片厚度、栅栏组织厚度、海绵组织厚度和角质层厚度,运用隶属函数值法对各树种的抗旱性能评分排序,将25种植物分为抗旱性极强树种、抗旱性较强树种、抗旱性一般树种和抗旱性较弱树种.
Objective]This study reported the leaf anatomical structure , stomatal characteristics , and the response mechanism of water adaptability of 25 shrubs on Tibetan Plateau , with an aim to provide a refer-ence beneficial to afforestation and selection of drought-resistant plants on the Tibetan Plateau and an at-tempt to outline how to screen excellent drought-resistant plants .[Method]Conventional paraffin section technique was used to make comparison with 12 indexes such as the thickness of leaf cuticle , upper epi-dermis , lower epidermis , palisade tissue , spongy tissue , and leaf thickness .The principal component a-nalysis and subordinate function were used to develop a system to analyze and evaluate the plant drought resistance .[Result and conclusion]The result showed that the leaves of all the 25 shrubs had typical xer-omorphic structures, and the maximum leaf thickness was up to 323.00 μm, 186.25 μm on average, and the maximum epidermal layer thickness was up to 4.8

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基于鄂尔多斯盆地长8超低渗透油藏地质与流体特征,应用数值模拟方法和等效网格加密技术建立了分段多簇压裂水平井单井数值模拟模型。利用数值试井的手段,研究了分段多簇压裂水平井的渗流规律及影响因素。结果表明:分段多簇压裂水平井渗流主要分为6个阶段,且表现出双重介质的特性;井筒储集系数的大小决定着垂直径向流是否出现,驼峰峰值随表皮系数的增大而增大;主裂缝导流能力主要对前期和中期渗流阶段影响较大,裂缝半长对无因次压力和压力导数的影响较小;改造区渗透率对无因次压力和压力导数曲线位置及形状产生较大影响;应力敏感的存在会使无因次压力和压力导数曲线上移,但各个渗流阶段不会发生明显的变化。
Based on the geological and fluid proprieties of Chang-8 ultra-low permeability res-ervoir ,a single well numerical simulation model of segmented multi-cluster fractured hori-zontal is built by using the method of numerical simulation and the technology of equivalent local grid refinement (EQ-LGR) .Application of the model ,flow regimes and its affecting factors of segmented multi-cluster fractured horizontal well are studied by using numerical well test .The result shows that the segmented multi-cluster fractured horizontal well has six flow stages and show s the characteristic of double media .Whether the vertical radial flow ap-pears depends on the size of the wellbore storage coefficient .Hump peak increases with the increase of skin factor .Flow conductivity of main fractures mainly affects the early and mid-dle flow stages .Fracture half-length is less effect on the dimensionless pressure and pressure derivative .Permeability of simulated zone has great influence on the locations

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苹果损伤是一种发生在水果采摘和产后处理阶段的不可避免的主要缺陷。为了快速有效地识别苹果的轻微损伤,以具有代表性的双色红富士苹果为研究对象,提出了一种以高光谱成像和最低噪声分离(MNF)变换的苹果轻微损伤识别检测方法。首先,使用高光谱成像系统获取苹果的可见-近红外波段(400~1 000nm)的图像,对比发现全波段的最低噪声分离变换比主成分分析(PCA)变换可获得更好的识别效果;其次,利用I-RELIEF算法对正常表皮和损伤区域的光谱进行分析得出权值系数图,依据该系数曲线挑选出了5个特征波段(560,660,720,820和960nm);最后,特征波段和最低噪声分离变换开发了损伤苹果的识别检测算法。利用该算法对80个正常苹果和含有不同时间阶段轻微损伤的苹果进行试验,损伤识别总体正确率为97.1%,试验结果表明,利用该方法和选取的特征波段可以快速有效地识别苹果的早期轻微损伤,为利用多光谱成像技术和最低噪声分离变换在线检测苹果轻微损伤奠定了基础。
Bruising is one of the major defects occurring on apple surface inevitably during postharvest handling and processing stage .To detect slight bruises on apples fast and efficiently ,a novel bruises detection algorithm based on hyperspectral imaging and minimum noise fraction transform is proposed .First ,the hyperspectral images in the visible and near-infrared (400~1 000 nm) ranges are acquired ,and MNF transform based on full ranges could obtain better detection performance compared to PCA transform ;Second ,five wavebands (560 ,660 ,720 ,820 and 960 nm) are selected as the effective wavebands based on the coef-ficient curve of I-RELIEF method conducted on spectra extracted from intact and bruise surface ;Third ,the bruises detection al-gorithm is developed based on the effective wavebands and MNF transform method .For the investigated 40 sound samples and 40 different time stage bruise samples ,the results with a 97 .1% overall detection rate are got .The recognition results indicat

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