研究超声波频率、强度、作用时间、传导耦合剂对氢溴酸高乌甲素经皮吸收的影响。方法:制备氢溴酸高乌甲素凝胶,测定在不同超声波作用频率、时间和强度下,以及不同耦合剂对透皮吸收速率和累积透皮吸收量的影响。结果:随着超声频率的增大,单位面积的累积透过量、稳态透皮速率都增大;导入强度可以在一定程度上影响药物的透皮吸收;超声波导入时间在一定范围内,可以促进药物的透皮吸收。结论:超声波导入效果与其频率、强度、作用时间等参数有关,可以通过改变参数来促进氢溴酸高乌甲素的透皮吸收。

OBJECTIVE To study the ultrasound, intensity,effective time, and different couplant on drug transdermal delivery in vitro. METHODS Preparated with lappaconitine hydrobromide gels, the influence of different ultrasound,intensity,effective time, and different couplants on the transdermal parameters per unit cumulative absorbing quantity (Q_(8hr)) and steady satepenetration rate (J_s) were determined. RESULTS The transdermal per unit (O_(8hr)) and (J_s) were increased with the ultrasoundfrequencies, ultrasound intensity and effective time could affect the action in some degrees on drugs transdermal delivery. CONCLUSION Sonophoresis s, including ultrasound,intensity,effective time, affected its action on drugs transdermal delivery. We can change the parametres to accelerate the transdermal absorption of lappaconitine hydrobromide.

近年来,原子吸收光谱法广泛用于食品中重金属含量的检测,该法具有检出限低、准确度高、选择性好及分析速度快等特点。本文综述了使用石墨炉原子吸收、火焰原子吸收和氢化物发生原子吸收3种原子吸收法测定粮食、蔬菜、水果和海产品中的铅、镉、铬、砷和汞等重金属元素的研究进展。此外,对原子吸收法在食品检测中的应用进行展望。

Atomic absorption spectrometry is widely used in detection of heavy metals in foods in recent years, which has low detection limit, high accuracy, good selectivity, fast analysis speed and so on. In this article, research advance in determination of heavy metals such as lead, cadmium, chromium, mercury and arsenic in cereals, vegeta-bles, fruits and seafoods were summarized by graphite furnace atomic absorption spectrometry, flame atomic absorption spectrometry and hydride generation atomic absorption spectrometry. In addition, application of atomic absorption method in food detection were prospected.

选取小麦(Triticum aestivum Linn.)为供试植物,利用盆栽试验研究了不同添加量的硅(0、50、100 mg·kg-1)对高硼(300 mg·kg-1)高盐(5 g·kg-1氯化钠)胁迫下植物生长以及对主要无机离子吸收的影响。结果表明,在硼盐联合胁迫下,硅能够提高小麦生物量,抑制对硼和钠的吸收,促进钾的吸收,降低植株钠钾比(Na/K),对钙、镁离子的吸收则没有显著影响。100 mg·kg-1硅处理对硼盐联合胁迫的缓解效果大于50 mg·kg-1硅处理。研究认为,硅能够通过抑制小麦对硼和钠的吸收,促进钾的吸收,缓解硼和盐联合胁迫对小麦生长的抑制作用。

Silicon(Si)has showed to improve the tolerance of plants to abiotic stresses. However, it is still unclear whether Si can enhance plant tolerance to combined stresses of excessive B and high salinity. A pot experiment was conducted with wheat(Triticum aestivum Linn.) grown in combined B(300 mg·kg-1), salinity(5 g·kg-1 NaCl), and Si(0 mg·kg-1, 50 mg·kg-1, and 100 mg·kg-1)to investigate the growth and ion uptake of wheat. Silicon increased wheat biomass and potassium(K)uptake, but inhibited the uptake of B and sodium(Na), thus re-ducing the tissue Na/K ratios. Silicon showed no significant effects on calcium(Ca)and magnesium(Mg)uptake. A greater alleviating effect of Si on combined stresses of B and salinity was observed under 100 mg Si·kg-1 than under 50 mg Si·kg-1. These results suggest that Si is able to alleviate the inhibition of wheat growth by combined stress of B and salinity via reducing B and Na accumulation and promoting K uptake.

目的：研究表明从菠萝叶中制备的总酚类成分具有抗氧化和调血脂作用。由于其灌胃后吸收较快，血中5 min即达峰值，因此本文通过急性糖脂负荷实验观察菠萝叶酚对糖脂吸收的影响。方法：利用小鼠单次灌胃建立糖脂负荷模型，观察给药后不同时间对餐后血糖、血脂和小肠脂肪酶的变化。结果：菠萝叶酚在一定程度上能够抑制甘油三酯和葡萄糖的吸收。在给药30 min后未见到明显的作用，但此时正常小鼠小肠脂肪酶活性受到明显抑制，并且对高脂所致小肠脂肪酶活性下降有一定的解抑制作用。结论：提示菠萝叶酚的抑制脂类吸收可能与脂肪酶活性有关；其对于餐后高糖高脂吸收的有一定调控作用。

This article was aimed to study the antioxidant and antihyperlipidemic effect of total phenolic composition prepared from pineapple (A nanas comosus L.) leave. It had a rapid absorption after intragastric administration and the principle ingredient, p-coumaric acid, reached the peak concentration after 5 minutes of administration. The mice model with single intragastric administration of lipid and glucose were used in the observation of changes on postprandial glucose, lipid and intestinal lipase at different time points after drug administration. The results showed that phenols of pineapple leave can inhibit triglyceride and glucose absorption in certain extent. No significant effect was observed on inhibition at 30 minutes after the phenol administration. However, the intestinal lipase activity was obviously inhibited in normal mice and the intestinal lipase activity decline caused by acute lipid consumption can be reversed. It was concluded that the phenols pineapple leave may inhib

综合论述了高含硫天然气净化厂对原料气中硫化氢气体吸收处理的方法。普光天然气净化厂在气体吸收溶剂上选择了最新的MDEA脱除溶剂,在工艺上采用了两级吸收的醇胺脱硫和级间冷却技术,充分实现了硫化氢气体的全部吸收。在硫化氢气体吸收过程中,普光天然气净化厂对工艺参数也进行了优化选择,最终实现了节能减排的总方针。

Comprehensive high sour natural gas purification plant was discussed in the feed gas processing method of hydrogen sulfide gas absorption.The new solvent MDEA removal was selected for gas absorption solvent , on craft adopt two-stage absorption between alcohol amine desulfurization and cooling technology , the full absorption of hydrogen sulfide gas was fully implemented.In the process of hydrogen sulfide gas absorption , Puguang gas purification plant for the optimization of process parameters was optimized , finally, the general policy of energy saving and emission reduction were achieved.