目的观察职业性慢性正己烷中毒患者神经肌电图(EMG)特征。方法选取职业性慢性正己烷中毒患者30例,分为轻、中、重度中毒3组,均在患者发病6个月时进行神经传导功能和肌电图检查并分析各指标的变化。结果 30例患者中,有7例患者腓总神经运动传导未引出动作电位,有2例患者腓肠神经未引出动作电位,其余患者所检神经均可引出。运动神经传导功能检查表现为运动神经传导速度(MCV)减慢、远端运动潜伏期(DML)延长和波幅降低,感觉神经传导功能检查表现为感觉神经传导速度(SCV)减慢和感觉神经动作电位波幅(SNAPA)降低。30例患者同一条神经左右侧上述各指标比较,差异均无统计学意义(P0.05)。3组患者左侧尺神经以及左、右侧腓总神经MCV分别比较,右侧尺神经DML比较,左、右侧的正中神经、尺神经和腓总神经波幅分别比较,左侧正中神经以及左、右侧尺神经SCV分别比较,左侧正中神经SNAPA比较,差异均有统计学意义(P0.05)。肌电图检查示,在安静状态下有67.7%出现自发电位,其中37.3%以复合重复放电为主,而纤颤电位和正锐波较少;肌肉小力收缩时有29.9%出现运动单位动作电位(MUAP)平均时限延长,14.9%未引出MUAP;肌肉大力收缩时募集电位多呈单纯相。结论职业性慢性正己烷中毒患者的EMG表现为感觉、运动混合型损害,神经轴索损害与脱髓鞘共存,左右对称发病,且有下肢神经运动传导受累程度较上肢严重等特点。
Objective To observe electromyography ( EMG) features in patients with occupational chronic n-hexane poi-soning.Methods According to the diagnostic conclusion , 30 patients with occupational chronic n-hexane poisoning were divided into mild, moderate and severe poisoning group .Nerve conduction test and EMG examination were conducted 6 months after the onset of the poisoning and the changes of each index were analyzed .Results Among 30 patients, peroneal nerve motor conductional action potentials were not elicited in 7 patients, sural nerve action potentials were not elicited in 2 cases, while others could be elicited in the rest of the patients .Motor nerve conduction function examination showed motor nerve conduction velocity (MCV) was slowed, distal motor latency (DML) was prolonged and the amplitude was decreased.Sensory conduction showed sensory nerve conduction velocity (SCV) was slowed and sensory nerve action po-tential amplitude ( SNAPA) was decreased .Analysis on parameters o