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双语推荐:Middle)

Teaching of speaking is weak in senior middle school mainly because of the neglect of speaking and the lack of appropriate teaching methods. This thesis puts forwards the application of Task-Based Language Teaching (TBLT), which aims at improving students' communicative competence by using language to finish certain tasks.
Teaching of speaking is weak in senior middle school mainly because of the neglect of speaking and the lack of appropriate teaching methods.This thesis puts forwards the application of Task-Based Language Teaching (TBLT),which aims at improving students' communicative competence by using language to finish certain tasks.

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恶性大脑中动脉梗死(malignant middle cerebral artery infarction,mMCAI)患者的转归很差,药物保守治疗的病死率高达80%.近几年发表的几项随机对照试验显示,偏侧颅骨切除术可显著降低mMCAI的病死率,是一种挽救患者生命的治疗措施,即使在年龄>60岁的患者.
The outcome of patients with malignant middle cerebral artery infarction (mMCAI) is very poor.The mortality of conservative medical treatment is as high as 80%.Several randomized controlled trials published in recent years have shown that hemicraniectomy can significantly reduce the mortality of mMCAI.It is a life-saving therapeutic measure for patients,even if so in patients older than 60 years of age.

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According to the characteristics of opencast coal resources and dragline technology system application in China, the structure and shifting step of transport passage are optimized in this paper. Typical coal trans-port passage is analyzed in aspects such as the internal dump occupation, dragline operation efficiency, coal transport distance, upper stripping distance and shifting quantities. The middle passage should be given priority in thick overburden open pit mine because the dragline system is only responsible for part stripping task. According to characteristics of middle passage, the transport passage is divided into par-allel climbing, vertical climbing and horizontal transport. In addition, the transport passage structure optimization model and shifting distance optimization model are established in this paper. The case study in Heidaigou open pit mine shows that, the parallel climbing height is accounted for about 60%of the total height, and reasonable shifting distances of th
According to the characteristics of opencast coal resources and dragline technology system application in China, the structure and shifting step of transport passage are optimized in this paper. Typical coal trans-port passage is analyzed in aspects such as the internal dump occupation, dragline operation efficiency, coal transport distance, upper stripping distance and shifting quantities. The middle passage should be given priority in thick overburden open pit mine because the dragline system is only responsible for part stripping task. According to characteristics of middle passage, the transport passage is divided into par-allel climbing, vertical climbing and horizontal transport. In addition, the transport passage structure optimization model and shifting distance optimization model are established in this paper. The case study in Heidaigou open pit mine shows that, the parallel climbing height is accounted for about 60%of the total height, and reasonable shifting distances of th

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目的利用大鼠自体血栓,在开放翼腭动脉(pterygopalatine artery,PPA)的情况下堵塞其大脑中动脉,造成大脑中动脉远端供血区的脑梗死模型。方法开放PPA,结扎颈外动脉(external carotid artery,ECA),将栓子通过颈总动脉(common carotid artery,CCA)血流将栓子冲大脑中动脉(middle cerebral artery,MCA)远端,造成梗死模型,按Bederson评分对其神经功能进行评分,TTC染色确定梗死体积。结果两手术组模型比较,评分均升高,且出现白色梗死区,经统计检测分析无明显差异。结论开放PPA大鼠自体血栓制造脑梗死模型可缩短手术时间,降低死亡率。
Objective To open pterygopalatine artery using autologous blood clot clogged the middle cerebral artery, resulting in cerebral infarction model of middle cerebral artery in the distal blood supply area.Methods Open PPA, ligation of ECA, embolus through CCA blood flow, rushed into the MCA distal embolus, cause infarction model. According to Bederson rating score the neural function.TTC staining to determine the infarction volume.Results Comparison of two operation models, scores were increased, and white infarcted area appears.There is no significant differences detected by statistical analysis.Conclusion Open PPA manufacturing cerebral infarction model rats of autologous blood clots could shorten the operation time, reduce the mortality rate.

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目的观察大脑中动脉闭塞(middle cerebral artery occlusion,MCAO)或狭窄的缺血性卒中患者的危险因素及血白细胞(white blood cell,WBC)、红细胞沉降率(erythrocyte sedimentation rate,ESR)和超敏C反应蛋白(high-sensitivity C-reactive protein,hs-CRP)的变化。方法 2005年1月~2011年1月期间北京友谊医院神经内科连续入选符合研究标准的262例缺血性卒中患者,其中98例MCAO(闭塞组)、23例大脑中动脉(middle cerebral artery,MCA)狭窄率70%~99%(重度狭窄组)、60例MCA狭窄率50%~69%(中度狭窄组)和81例MCA狭窄率50%(轻度狭窄组)。比较四组患者的危险因素及入院24h血WBC、ESR和hs-CRP等指标。结果闭塞组、重度狭窄和中度狭窄组糖尿病患病率明显高于轻度狭窄组(P分别为0.008、0.044和0.018),其他危险因素在四组间比较差异均无显著性。闭塞组WBC、ESR和hs-CRP水平均高于轻度狭窄组(P分别为0.005、0.002和0.001);重度狭窄组ESR亦高于轻度狭窄组(P=0.026)。结论 MCA闭塞和重度狭窄的缺血性卒中患者血WBC、ESR和hs-CRP水平高于MCA轻度狭窄患者。
@@@@Objective To analyze the risk factors and the changes of white blood cell(WBC), erythrocyte sedimentation rate(ESR) and high-sensitivity C-reactive protein(hs-CRP) in ischemic stroke patients with middle cerebral artery occlusion(MCAO) and stenosis. @@@@Methods From January 2005 to January 2011, 262 unselected ischemic stroke patients who were admitted to Department of Neurology in Beijing Friendship Hospital were enrolled into our study. It included 98 patients with MCAO(MCAO group), 23 patients with 70%~99% stenosis in middle cerebral artery(MCA)(severe stenosis group), 60 patients with 50%~69% stenosis in MCA(moderate stenosis group), and 81 patients with less 50% stenosis in MCA(mild stenosis group). The risk factors and WBC, ESR and hs-CRP in 24 h after admission were compared among four groups. @@@@Results The proportion of history of diabetes mellitus in the MCAO group, severe stenosis group and moderate stenosis group was significantly higher than that in the mild stenosis

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恶性大脑中动脉梗死(malignant middle cerebral artery infarction,mMCAI)患者在重症监护室内接受保守治疗时的病死率高达41%~78%,恶性脑水肿引起的小脑幕切迹疝形成是导致患者死亡的最常见原因.一些证据支持偏侧颅骨切除术用于mMCAI患者的治疗.在做出手术治疗决策之前,必须对患者进行支持性和辅助性治疗,因此,mMCAI的预测和重症监护治疗具有十分重要的意义.文章对mMCAJ的预测因素和重症监护治疗进行了综述.
Mortality of patients with malignant middle cerebral artery infarction (mMCAI) is as high as 41% to 78% with the conservative treatment in the intensive care unit.Malignant edema caused tentorial herniation is the most common cause of resulting in the death of patients.Some evidence supports the hemicraniectomy for the treatment of patients with mMCAI.The patients must receive supportive and adjuvant therapies before surgical decision making.Therefore,the prediction and intensive care of mMCAI have a very important significance.This article reviews the predictive factors and intensive care of mMCAI.

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中东呼吸综合征冠状病毒(Middle East Respiratory Syndrome-Coronavirus,MERS-CoV)是继SARS冠状病毒(SARS-CoV)之后发现的一种能引起人严重急性呼吸道疾病且具有高致死率的新型病毒。目前还没有有效的抗病毒治疗药物或疫苗。现已从主要流行的中东地区逐渐蔓延至多个国家,具有全球流行的潜在趋势,引起了世界各国的极大关注及众多的调查研究。本文主要对MERS-CoV的传播源及途径、致病机理和抗病毒药物及疫苗等的研究进展做一综述,以期对研制特异的抗病毒药物及疫苗和实施切实有效的预防及控制措施提供参考。
Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) is a novel coronavirus which can cause severe acute respiratory illness with a high mortality rate .There is no proven medication or vaccine for MERS-CoV .Currently MERS-CoV has spread from the main epidemic area ,the Middle East area ,to many other countries including United States of America and has the potential of global endemic .It has raised global public health concerns regarding the current situation and its future evolution .This review will mainly focus on the research progress of MERS-CoV about the animal reservoir and transmission , infection mechanisms and development of anti-viral drugs or vaccine .The goal is to provide with useful references to the devel-opment of specific drug and vaccine and an effective control and prevention of M ERS-CoV infection .
颅内动脉粥样硬化性疾病(intracranial atherosclerotic disease, ICAD)是国人缺血性卒中主要原因,防治难点在于卒中高危人群筛查及有效治疗方法的选择(药物治疗/介入治疗)。3.0 T HR MRI具有在体、无创、无电离辐射等优势,能够从管壁结构及斑块特性的视角筛选大脑中动脉(middle cerebral artery, MCA)粥样硬化狭窄的卒中高危因素,观察疾病进程和临床疗效,具有潜在的预判介入手术获益人群的优势,临床应用前景广阔。目前HR MRI在MCA狭窄患者评估中的应用研究主要集中在方法学可行性、诊断与鉴别诊断、病因学等3方面,缺乏临床疗效评估及预后因素分析(尤其是术后再狭窄)相关实践,值得深入探讨。
Intracranial atherosclerotic disease (ICAD) of a major intracranial artery, including middle cerebral artery (MCA), basilar artery, is the most common causes of stroke and is associated with a high risk of recurrent stroke in China. The difficulty to treatment these high-risk disease is to identify high-risk stroke subgroups and to develop more effective treatments (aggressive medical therapy/endovascular therapy). With the benefits, including non-invasive, in vivo, and no-ionizing radiation, 3.0 Tesla high-resolution magnetic resonance imaging (HR MRI) could be used to stratify high-risk patients, monitor progression of disease, and evaluate clinical efficacy, based on MCA wall structure and plaque characteristic. HR MRI has the latency of predicting high-risk patients benefit from endovascular therapy, having a broad application prospect during psot-SAMMPRIS era. The current research on MCA stenosis using HR MRI focuses on methodology, diagnosis and differential diagnosis,
对于胰腺多中心肿瘤过去多采取全胰切除术,术后不可避免地出现严重胰腺内、外分泌功能障碍,严重影响患者的生活质量.近年来,保留胰腺功能的各种胰腺切除术越来越多地被报道,如中段胰腺切除术、胰头切除术、胰体尾切除术等[1-2],但保留中段的胰腺切除术(middle-preserving pancreatectomy,MPP)罕见报道.我们从2011年1月至2013年3月成功实施2例该类手术,患者术后胰腺内外分泌功能良好.现报道如下并结合文献展开讨论.
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颅内动脉狭窄是中国人群急性缺血性卒中患者最常见的血管病变,其中以大脑中动脉(middle cerebral artery,MCA)狭窄最为多见.无症状MCA狭窄的治疗以控制危险因素和药物治疗为主,预后较好,他汀类药物能减少新发卒中事件;有症状MCA狭窄的治疗方案主要是控制危险因素、药物治疗和支架置人治疗.目前认为,抗凝药在治疗MCA狭窄方面并不优于抗血小板药,但双联抗血小板药是否优于单药治疗以及支架置入治疗是否优于药物治疗尚无定论.有症状MCA狭窄的预后较差,急性期预后主要取决于影像学特征,卒中复发风险主要与MCA狭窄情况相关.将来的研究应着重针对双联抗血小板药是否优于单药治疗、支架置入治疗是否优于药物治疗以及MCA狭窄程度与急性期预后和卒中复发风险之间的关系.
Intracranial arterial stenosis is the most common vascular lesions in patients with acute stroke in Chinese population,and most of them are middle cerebral artery (MCA) stenosis.The treatment of asymptomatic MCA stenosis is mainly to control the risk factors and treat with drugs,and the prognosis is better.Statins can reduce new stroke events.The treatment programs of symptomatic MCA stenosis are mainly to control the risk factors,treat with drugs and stenting.Now it is considered that anticoagulants are not superior to antiplatelet drugs in the treatment of MCA stenosis,but whether dual antiplatelet drugs are superior to monotherapy and stenting remains to be determined.The prognosis of symptomatic MCA stenosis is poor.The prognosis of acute phase mainly depends upon imaging features,and the risk of recurrent stroke is primarily associated with the MCA stenosis.Future research should focus on whether dual antiplatelet therapy is superior to monotherapy,and whether stenting is superior