目的：探讨苯甲酸阿格列汀光学纯度与（R）-3-氨基哌啶双盐酸盐光学纯度之间的关系。方法：通过纯度测定方法检测（R）-3-氨基哌啶双盐酸盐的光学纯度,评价苯甲酸阿格列汀的光学纯度。结果与结论：（R）-3-氨基哌啶双盐酸盐光学纯度与苯甲酸阿格列汀之间的光学纯度有对应关系,通过控制（R）-3-氨基哌啶双盐酸盐光学纯度大于98%即可保证苯甲酸阿格列汀光学纯度合格。

Objective:To discuss the relationship of optical purity between alogliptin benzoate and (R)-3-amino piperidine double hydrochloride. Methods:By the optical purity determination method test (R)-3-amino piperidine double hydrochloride, evaluation of optical purity of alogliptin benzoate.Results and conclusion:There is corresponding optical purity relationship of between alogliptin benzoate and (R)-3-amino piperidine double hydrochloride. By controlling the optical purity of (R)-3-amino piperidine double hydrochloride is more than 98%can be sure qualified the optical purity of alogliptin benzoate.

目的：采用两种方法测定盐酸青藤碱纯度，并建立其不确定度评定方法。方法采用高效液相色谱法（ HPLC）对盐酸青藤碱纯度进行测定，并依据标准物质技术规范及相关计量技术规范要求，对HPLC法测定过程的不确定度进行了系统分析，并采用酸碱非水滴定法对盐酸青藤碱纯度值进行验证。结果采用HPLC法测定盐酸青藤碱纯度的标准值及其不确定度为99．87％±0．41％（k＝2，P＝0．95）。酸碱非水滴定法测定纯度值为99．88％，在不确定度范围之内。结论采用HPLC与酸碱非水滴定法联合测定盐酸青藤碱纯度及不确定度评定结果准确可靠，避免了采用一种技术带来的分析方法缺陷，有利于提高盐酸青藤碱的质量评价与控制水平，同时对盐酸青藤碱纯度标准物质的研制提供了科学依据。

OBJECTIVE To measure the purity of Sinomenine Hydrochloride by two different principles meth-ods and establish a method for uncertainty evaluation .METHODS According to Technical Norm of Primary Refer-ence Material and Technical Norm of Measuremen , HPLC was selected to deterimiante the purity of Sinomenine Hydrochloride ,and the uncertainty evaluation was analyzed systematically .Sinomenine Hydrochloride purity value was verified by the non-aqueous acid-base titration.RESULTS By using HPLC method ,The standard value and un-certainty of Sinomenine Hydrochloride purity was 99.87%±0.41%(k=2,P=0.95).The standard value of Sino-menine Hydrochloride purity was 99.88% by the non-aqueous acid-base titration within the uncertainty range.CONCLUSION The valuation and uncertainty evaluation in Purity determination of Sinomenine Hydrochlo-ride by using HPLC and non-aqueous acid-base titration is accurate and reliable , and avoids the defect by using a single analysis method ,it is helpfu

在我国丁醇有着较好的市场，目前国内丁醇厂家20余家，随着生产厂家的每年增加，对丁醇纯度的要求也逐渐提高。本文结合化工实际生产对影响丁醇纯度的要素进行阐述，并针对如何提高正丁醇纯度提出了一些建议。

There was a good market prospect for butanol in china. At present, it has been more than 20 butanol manufacturers. With an annual increase of manufacturers,butanol purity requirements also gradually improved. In this paper,the factors of butanol purity in the actual chemical production were presented. And some suggestions were put forward on how to improve the purity of butanol.

以钛白生产中产生的废盐为原料,采用水热法合成制备了高纯MnO2纳米棒,研究了不同反应条件对产品纯度和产率的影响.以纯度和产率为指针,确定了制备高纯MnO2纳米棒的最佳工艺条件,并对样品进行了XRD、FT-IR、SEM、ICP表征.研究结果表明,MnO2纳米棒的纯度随水热反应pH增大而增大,当pH为2.0时,制得的MnO2纳米棒纯度最大,继续增大pH,样品纯度下降,MnO2纳米棒的产率随水热反应pH增大而增大,当pH为4.0时,产率最大,继续增大pH,产率下降;当NaCl的加入量为0.08 g时,纯度和产率同时达到最大;MnO2纳米棒纯度几乎不随NaClO3加入量的变化而变化,而产率随着NaClO3加入量的增加而增加.

High purity manganese dioxide nanorods were prepared from titanium oxide abraum salt by hydro-thermal method .In this experiment , the effects of different reaction conditions on the purity and yield were stud-ied.The purity and yield were used to determine the best conditions .Meanwhile, XRD, FT-IR, SEM, ICP were used to characterize the samples .The results show that the purity of manganese dioxide nanorods increases slightly with the increase of pH , the purity reaches the highest at the pH of 2.0, while the purity reduces as the pH continue to increase .The yield of manganese dioxide nanorods increases with the increase of pH , and the yield reaches the highest at the pH of 4 .0 , while the yield reduces as the pH continue to increase .The purity and the yield reach the highest when the amount of sodium chloride is 0.08 g.With the increase of the dosage of sodium chlorate , the yield of manganese dioxide nanorods increases , while the purity is hardly changed .

MTBE产品纯度是考量MTBE产品质量的重要指标,中化泉州石化有限公司13万吨/年MTBE装置在开工初期产品纯度一度偏低,满足不了全厂生产欧Ⅳ标准汽油的需要。本文剖析了泉州石化MTBE装置开工初期产品纯度低的原因,并提出了有效的解决办法。

The purity of MTBE was the important index of its product quality .The 130 000 t/a MTBE of Sinochem Quanzhou Petrochemical Co ., Ltd.had a low purity of its product at early start , and can not meet the demand of produce Euro-ⅣEmission standards gasoline in the factory .The reasons for the low purity of MTBE unit at the beginning were analyzed , and some effective solutions were put forward .