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双语推荐：FSV

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目的：从电力线载波通信系统中提取随机脉冲噪声并分析其来源。方法建立一个简单的检测随机噪声的测试系统。结果 FSV 方法可以成功地识别热水壶在电力线上造成的随机脉冲噪声，同时也证明了统计分析的方法对于识别随机脉冲噪声效果不佳。结论可以通过对 MAF-FSV 方法结果设定阈值来识别低压电力线载波通信系统中的随机脉冲噪声，进而可以确定低压电力线网络拓扑结构的改变。
Objective To extract the asynchronous impulsive noise from the power communication line and obtain the source of particular kind of noise. Methods A simple measurement system was constructed to detect the asynchronous im-pulsive noises. Results The Feature Selective Validation (FSV) method was able to successfully recognize the impulsive noise produced in the power line by the connection of a kettle. Meanwhile, the statistical analysis was proved useless in the recognition of asynchronous impulsive noise. Conclusion The asynchronous impulsive noise in the low-voltage power com-munication line could be recognized by setting threshold values for the results of MAF-FSV method, and the change in the topological structure of the low-voltage power line network could then be determined.

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目的 探讨老年慢性功能性便秘(FC)患者肛门直肠功能和焦虑抑郁情绪的性别差异.方法 选择老年女性FC患者27例(老年女性患者组),老年男性FC患者20例(老年男性患者组),老年健康女性对照28例(老年女性对照组),老年健康男性对照24例(老年男性对照组).采用肛门直肠测压法和心理测试法,比较各组肛门直肠功能和焦虑抑郁情绪的不同及相关性,并比较性别差异.结果 与老年女性对照组比较,老年女性患者组的最大缩窄压(MSP)、直肠肛管压差降低(P＜0.05或＜0.01),模拟排便时肛管剩余压、初始感觉阈值(FSV)、排便感觉阈值(DSV)和最大耐受量(MTV)均升高(P＜0.01).与老年男性对照组比较,老年男性患者组的肛管剩余压也升高(P＜0.05),直肠肛管压差降低(P＜0.05),FSV、DSV、MTV也均升高(P＜ 0.01或＜0.05).老年女性患者组的MSP、模拟排便时直肠收缩压和直肠肛管压差低于老年男性患者组(P＜0.05或＜0.01),肛管剩余压和直肠感觉阈值高于老年男性患者组,但差异无统计学意义(P＞0.05).老年女性对照组的直肠静息压(RRP)、直肠收缩压、直肠肛管压差低于老年男性对照组(P＜0.01);FSV高于老年男性对照组(P＜0.01).老年女性患者组的Zung焦虑自评量表(SAS)和Zung抑郁自评量表(SDS)评分均显著高于老年
Objective To investigate the gender differences of anal rectal function and depression and/or anxiety in elderly patients with functional constipation (FC).Methods Twenty-seven elder female FC patients (elder female patients group),20 elder male FC patients (elder male FC patients group),28 elder healthy female (elder healthy female group) and 24 elder healthy male (elder healthy male group) were selected.The gender differences and correlation of anal rectal function and psychological factors were compared in elderly patients and control group,by using anorectal manometry and psychological testing methods.Results Compared with elder healthy female group,maximum squeeze pressure (MSP),anorectal pressure decreased in elder healthy male group(P ＜ 0.05 or ＜ 0.01),anal canal overpressure,first sensation volume(FSV),defecating sensation volume(DSV),maximum tolerable volume(MTV) increased in elder female patients group (P＜ 0.01).Compared with elder male healthy group,anal canal e

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目的：探讨波生坦治疗儿童先天性心脏病（CHD）相关肺动脉高压（PAH）的临床疗效。方法选取医院2012年至2013年收治的66例CHD患儿，其中左向右分流组（A组）38例，功能性单心室（FSV）组（B组）28例，均口服波生坦治疗，随访并评估临床疗效与不良反应。结果 A组患儿治疗1~3个月后肺动脉高压均明显下降，心功能明显改善，差异有统计学意义（ P﹤0.05）。B组患儿治疗前心功能Ⅳ，Ⅲ，Ⅱ级构成比分别为32.14%（9/28），46.43%（13/28），21.43%（6/28），末次随访各级构成比分别为0，21.43%（6/28），71.43%（20/28），另2例（7.14%）为心功能Ⅰ级，差异均有统计学意义（ P﹤0.05）；治疗前脉搏血氧饱和度（SpO2）为（79±5）%，末次随访时SpO2为（85±5）%，差异有统计学意义（ P﹤0.05）；治疗前B组患者颜面部水肿14例、胸腔积液15例、心包积液9例，末次随访时颜面部水肿2例、胸腔和心包积液各1例，差异有统计学意义（ P﹤0.05）。结论波生坦治疗儿童CHD相关PAH疗效良好，值得临床推广。
Objective To investigate the clinical effect of bosentan in treating child congenital heart disease(CHD)associated pulmonary arterial hypertension(PAH). Methods 66 children patients with CHD in our hospitals from 2012 to 2013 were selected as the research subjects,including 38 cases of left to right shunt(group A)and 28 cases of functional single ventricle(FSV,group B),and treated by oral bosentan. The clinical effects and adverse reactions were followed up and evaluated. Results PAH after 1-3 months therapy in the group A was decreased obviously and the cardiac function was significantly improved,the difference showed statistical significance ( P ﹤ 0. 05);the constituent ratio of heart function grade Ⅳ,Ⅲ,Ⅱ before treatment in the group B was 32. 14%(9/28),46. 43%(13/28) and 21. 43%(6/28) respectively,the constituent ratio of various grades at last follow-up was 0,21. 43%(6/28) and 71. 43%(20/28)respectively,other 2 cases(7. 14%)were the cardiac function grade Ⅰ,the diff

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目的：探讨实时三维超声心动图评价功能性单心室患儿心功能和同步性的应用价值。方法选取功能性单心室患儿20例，正常儿童20例，Q‐lab软件分析并计算比较主心腔的舒张末期容积、收缩末期容积、射血分数、节段位移和圆心位移值以及各项同步性各项参数。结果①单心室患儿舒张末期容积及收缩末期容积比正常儿童明显增大，而射血分数却显著降低；②单心室患儿各节段的位移均低于正常儿童；③单心室患儿 Tmsv16‐SD、Tmsv16‐SD％、Tmsv16‐Dif、Tmsv16‐Dif％、Tmsv12‐SD、Tmsv12‐SD％，Tmsv12‐Dif、Tmsv12‐Dif％、Tmsv6‐SD、Tmsv6‐SD％、Tmsv6‐Dif、Tmsv6‐Dif％较正常儿童有明显延长；④同步性指标和心功能相关性较好，Tmsv16‐SD％与 EF相关性最好（ r ＝‐0．774，P ＜0.001）。结论 Tmsv16‐SD％与EF相关性最好，是反映心肌运动同步性的理想指标。
Objective To explore the value of three‐dimensional echocardiography for assessment of ventricular function and synchronicity in functional single ventricle (FSV) .Methods 3DE data were acquired in 20 patients with FSV and 20 age‐matched normal children ,then ,end‐diastolic volume (EDV) ,end‐systolic volume (ESV) ,ejection fraction (EF) ,ex‐cursion ,ball excursion and indexes of ventricular synchronicity were compared by Q‐lab software .Results ① EDV and ESV were significantly higher and EF were significant significantly lower in FSV group ;②Excursion of various segments was lower in FSV group ; ③ The values of Tmsv16‐SD , Tmsv16‐SD% , Tmsv16‐Dif , Tmsv16‐Dif% , Tmsv12‐SD , Tmsv12‐SD% ,Tmsv12‐Dif , Tmsv12‐Dif% , Tmsv6‐SD% , Tmsv6‐SD% , Tmsv6‐Dif , Tmsv6‐Dif% were significantly prolonged in FSV ;④Most indexes of LV synchronicity had good correlation with ventricular function ,especially Tmsv16‐SD% ( r =‐0 .774 ,P<0.001) .Conclusion Tmsv16‐SD% ,best cor

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目的：探讨老年功能性便秘（FC ）患者肛门直肠功能性别差异及其心理影响因素。方法采用肛门直肠测压法，比较老年FC患者（FC组）与健康对照者（对照组）肛门直肠功能的性别差异；同时以两种精神‐心理量表对其焦虑、抑郁情绪进行测试。结果 FC组男女性患者模拟排便时肛管压力下降程度均显著低于对照组，直肠感觉阈值均显著增高，并且女性患者的最大缩榨压（MSP）、直肠收缩压和直肠肛管压差低于男性。男女性患者的Zung焦虑自评量表（SAS）、Zung抑郁自评量表（SDS）评分均明显高于对照组，女性患者的SAS评分高于男性。SAS、SDS评分与直肠肛管压差呈负相关，与初始感觉阈值（FSV）呈正相关。结论肛门直肠功能障碍与焦虑、抑郁情绪参与老年FC的发病，并且二者呈相关性。老年女性患者较男性存在更严重的焦虑情绪及肛门直肠动力异常。
Objective To investigate the gender differences and psychological influencing factors for anal rectal function in senile patients with functional constipation (FC) .Methods The gender differences and correlation of anal rectal function and psychological factors were compared in elderly patients and control group by anorectal manometry and psychological testing methods .Results The anal pressure drops of analog defecation of elderly female and male patients were attenuated and the rectal sensation thresholds increased compared with that of control group ,and the maximal squeezing pressure ,the rectal defecation pressure and anorectal pressure difference of elderly female patients were attenuated compared with that of elderly male patients .The SAS and SDS stand‐ard score of elderly female and male patients were significantly higher than that of control group .The SAS standard score of elderly female patients were higher than elderly male patients .SAS and SDS were negatively

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目的综合了解树鼩的分泌蛋白的信息。方法利用真核生物分泌蛋白预测流程EuSecPred 2.0对树鼩的分泌蛋白进行全基因组预测,并对获得的分泌蛋白及所携带的信号肽进行系统分析。结果树鼩全基因组蛋白基因中鉴定获得279个分泌蛋白,占基因组全部编码基因的7.2%。对其功能和结构域进行注释分析,发现了以水解酶类、行使蛋白结合与离子结合功能蛋白质及初级代谢过程相关蛋白为主的分泌蛋白。氨基酸组成分析表明,树鼩分泌蛋白及其信号肽主要由疏水性氨基酸组成,信号肽剪切位点有部分亲水性氨基酸的存在。基序分析发现,分泌蛋白信号肽中未存在保守基序,而分泌蛋白内部存在GxHxCGG[FSV]L[IV][RAS][EP]D[WF]VLTAAHC、[KG]PPGV[YF]T[RK][VI][SC]x[YF][VL][DS]WIQx[TV][MI][RK]、[DT][SA][CF][QK]GDSGGPLVCNGV[LA]QG[IL]V、GY[HL][FL]CGG[SAT]L[ILV]S[EDP][CR]WV[LV][TS]AAHCF、N[IV][FI]FSP[LV]S[IV][SA][TA]ALAMLSLG[AT]xNDTLTQ[IL]L[EQ][GV]LGF[ND]LT[ES]T[SP]E 5种基序。结论在全基因组范围对树鼩分泌蛋白进行预测分析,有助于进一步研究树鼩机体功能调控机制及动物模型的开发。
Objective To better understand the information of secreted proteins of Tupaia Chinensis.Methods The internet-based software EuSecPred 2.0 and other mapping software were collectively used to predict and analyze the genome-wide secreted proteins .Results There were 279 secreted proteins , accounting for 7.2% of the total proteins encoded by genome sequences .The function and structure of the domain annotation analysis found that they were mainly hydrolases , protein/ion binding proteins and the primary metabolic process-associated proteins .Amino acid composition analysis showed that the signal peptide secreted proteins were mainly composed of hydrophobic amino acids , and there existed some hydrophilic amino acids in the signal peptide cleavage site .Motif analysis revealed no presence of conserved motifs in signal peptide , however , five kinds of motifs existed inside the secreted proteins .Conclusion Genome-wide predictive analysis of secreted proteins of tree shrews is helpful for

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